中国实用口腔科杂志2024，Vol.17Issue(3)：365-371,7.DOI:10.19538/j.kq.2024.03.018
脂肪干细胞在牙周组织再生中应用研究进展
Research progress on the application of adipose stem cells in periodontal tissue regeneration
摘要
Abstract
Periodontitis is a common inflammatory oral disease that causes loss of periodontal supporting tissues includ-ing gingiva,alveolar bone,periodontal ligaments and cementum,and even tooth loss,severely affecting patients'quality of life.The ultimate goal of periodontal treatment is to regenerate periodontal tissues and restore the normal physiological structure and function of periodontal tissues,and stem cell-based tissue regeneration engineering technology is currently an important technical means to achieve periodontal tissue regeneration.Adipose-derived stem cells(ADSCs)are mesen-chymal stem cells derived from adipose tissue,which have the potential for self-replication and multi-directional differ-entiation and are involved in tissue regeneration,revascularization and immune regulation,and are one of the ideal seed cells for periodontal tissue regeneration.This review describes the research progress on the application of ADSCs in peri-odontal tissue regeneration in recent years,in order to provide research direction for periodontal tissue regeneration thera-py-关键词
脂肪干细胞/间充质干细胞/牙周组织再生/骨再生/免疫调节Key words
adipose-derived stem cells/mesenchymal stem cells/periodontal tissue regeneration/bone regeneration/im-munomodulation分类
医药卫生引用本文复制引用
徐名颉,王锦衡,谢旭东,许春梅,王骏..脂肪干细胞在牙周组织再生中应用研究进展[J].中国实用口腔科杂志,2024,17(3):365-371,7.基金项目
国家自然科学基金面上项目(82071127 （）
82270990) （）
四川省重点研发计划(2023YFS0032) （2023YFS0032）
四川省自然科学基金(2022NSFSC0795) （2022NSFSC0795）
四川大学华西口腔医院人才队伍建设科研经费资助项目(RCDWJS2020-12) （RCDWJS2020-12）
四川大学华西口腔医院探索与研发项目(RD-03-202403) （RD-03-202403）
