重症急性胰腺炎治疗面临的挑战与对策OA北大核心CSTPCD

In recent years,with the development of minimally invasive and endoscopic technology,the treatment concept of Severe acute pancreatitis(SAP)is constantly updated.The"step-up approach"has become the mainstream treatment mode of SAP and has significantly improved its cure rate.Although treatment concepts and techniques are increasingly updated,there are still some challenges and controversies in the treatment of SAP,such as the principle of fluid resuscitation,the management of abdominal compartment syndrome(ACS),the timing and mode of surgical intervention for infected pancreatic necrosis(IPN),the advantages and disadvantages of endoscopic and surgical debridement,and the necessity of open debridement.All the above problems need to be validated by further high-quality clinical studies.Multidisciplinary team is crucial,and establishing standardized pancreatic disease centers can benefit more SAP patients.