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升阶梯时代对重症急性胰腺炎外科干预的再认识OA北大核心CSTPCD

Further understanding of surgical intervention for severe acute pancreatitis in the era of step-up approach

中文摘要英文摘要

近十余年来,创伤递升式治疗(step-up approach)已经成为重症急性胰腺炎(SAP)外科干预的主流模式.但SAP病情复杂多变,加之微创理念和技术的飞速发展,在step-up approach的大背景下,如何能够让病人从外科干预中受益最大化仍然值得深入思考.感染性胰腺坏死(IPN)分型的确立具有重要的临床意义,即对于不同类型IPN的治疗不能单纯局限于一种策略,针对部分病例可打破传统,采用跨越式干预模式,以此作为step-up approach的补充与完善.多学科综合治疗协作组(MDT)模式应贯穿于SAP个体化治疗的始终.外科医生在SAP的个体化综合治疗中仍然发挥了不可替代的重要作用.现阶段,仍要结合病人具体情况、学科和医生的技术特点制定个体化、精准化和微创化的干预方案.开放性清创作为step-up approach策略中的重要组成部分,应在合理的指征与时机下有计划开展,不可偏废.在升阶梯治疗的时代下,应遵循递升式与跨越式策略按需切转换,外科式与内镜式干预方式并重,建立高效统一的MDT诊疗平台,从而进一步提高SAP的整体治愈率.

In the past decade or so,the step-up approach has become the mainstream surgical intervention model for severe acute pancreatitis(SAP).However,the complexity and variability condition of SAP,coupled with the rapid development of minimally invasive concepts and technologies,make it worthwhile for us to deeply consider how to maximize the benefits of surgical intervention for patients in the context of step-up approach.The establishment of subtypes for infectious pancreatic necrosis(IPN)has important clinical significance,which means that the treatment of different types of IPN cannot be limited to a single strategy.In some cases,traditional intervention models can be broken and a leapfrog intervention model can be adopted as a supplement and improvement to the step-up approach.The multidisciplinary tream(MDT)model runs through the entire process of individualized treatment in SAP,surgeons still play an irreplaceable role in the personalized comprehensive treatment of SAP.At present,we still need to develop personalized,precise,and minimally invasive intervention plans based on the specific situation of patients,disciplines,and the technical characteristics of doctors.Open debridement,as an important component of the step-up approach,should be carried out in a planned manner with reasonable indications and timing,and should not be neglected.In the era of stepwise treatment,it is necessary to follow the strategy of switching between progressive and leapfrog interventions as needed,emphasizing both surgical and endoscopic intervention methods,and establishing an efficient and unified MDT diagnosis and treatment platform,to further improve the overall cure rate of SAP.

王刚;徐德全;周昊昕

哈尔滨医科大学附属第一医院胰胆外科肝脾外科教育部重点实验室,黑龙江哈尔滨 150001哈尔滨医科大学附属第一医院急诊外科,黑龙江哈尔滨 150001

临床医学

重症急性胰腺炎升阶梯治疗感染性胰腺坏死多学科协作治疗外科干预

severe acute pancreatitisstep-up approachinfected pancreatic necrosismultidisciplinary treamsurgical intervention

《中国实用外科杂志》 2024 (005)

516-520 / 5

国家自然科学基金项目(No.82370651,No.82070657)

10.19538/j.cjps.issn1005-2208.2024.05.06

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