中国实用外科杂志2024，Vol.44Issue(5)：524-529,6.DOI:10.19538/j.cjps.issn1005-2208.2024.05.08
重症急性胰腺炎的早期液体复苏和器官保护
Early fluid resuscitation and organ protection in severe acute pancreatitis
摘要
Abstract
Fluid resuscitation and organ function protection are two key steps in the early treatment of severe acute pancreatitis(SAP).Fluid resuscitation should be evaluated immediately upon diagnosis of SAP,especially in patients with shock or dehydration.Equilibrium fluid is the preferred recommended fluid for resuscitation,and lactate Ringer's fluid is commonly used.Albumin may be used when receiving large amounts of crystalloid.The initial liquid rate and dosage of fluid resuscitation should be determined in combination with the resuscitation target and monitoring,and titrated liquid resuscitation should be carried out by the principles of individualization,precision,and restriction to avoid overload.Early organ dysfunction affects the prognosis of SAP,and early prophylaxis,detection,intervention,and protection are emphasized to prevent the occurrence and progression of multiple organ dysfunction.Prevention is more important than treatment.Early monitoring in the ICU,standardized fluid resuscitation,organ function support and comprehensive medical treatment are more important.Management measures include etiological treatment,early fluid resuscitation and circulation support,regulation of inflammatory response,improvement of intestinal barrier function,blood purification therapy,early respiratory support,kidney support,anticoagulation,brain protection,infection control,analgesia and sedation.关键词
重症急性胰腺炎/液体复苏/器官保护/器官功能障碍Key words
acute severe pancreatitis/fluid resuscitation/organ protection/organ dysfunction分类
医药卫生引用本文复制引用
李双玲,谢旻,杨尹默..重症急性胰腺炎的早期液体复苏和器官保护[J].中国实用外科杂志,2024,44(5):524-529,6.基金项目
中央高水平医院临床科研业务费资助项目(No.2022CR43) （No.2022CR43）
国家临床重点专科建设项目(No.2023-141) （No.2023-141）
