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哺乳动物卵母细胞老化的相关机制研究进展

许庆龙 姚顺发 张君正 曹立朋 陈璇 金一

中国畜牧杂志2024,Vol.60Issue(6):60-66,7.
中国畜牧杂志2024,Vol.60Issue(6):60-66,7.DOI:10.19556/j.0258-7033.20230811-06

哺乳动物卵母细胞老化的相关机制研究进展

Research Progress on the Mechanism Related to the Aging of Mammalian Oocytes

许庆龙 1姚顺发 1张君正 1曹立朋 1陈璇 1金一1

作者信息

  • 1. 延边大学农学院,吉林延吉 133002
  • 折叠

摘要

Abstract

The aging of mammalian oocytes is a complex and irreversible biological process,mainly characterized by parthenogenetic activation and apoptosis.Aging will cause the morphological and structural changes of oocytes and the decrease of organelle function,resulting in the decline of oocyte quality,which directly affects the results of fertilization and embryonic development.At present,there are more and more extensive studies on the aging characteristics,influencing factors and how to delay the aging of oocytes cultured in vitro.This paper reviews the related studies on the characteristics of oocyte aging,influencing factors and delaying oocyte aging in recent years,in order to provide some reference for improving oocyte aging and optimizing assisted reproductive technology.

关键词

哺乳动物/卵母细胞/细胞老化/氧化应激/抗氧化剂

Key words

Mammals/Oocytes/Cell senescence/Oxidative stress/Antioxidants

分类

农业科技

引用本文复制引用

许庆龙,姚顺发,张君正,曹立朋,陈璇,金一..哺乳动物卵母细胞老化的相关机制研究进展[J].中国畜牧杂志,2024,60(6):60-66,7.

基金项目

国家自然科学基金(31960659) (31960659)

中国畜牧杂志

OA北大核心CSTPCD

0258-7033

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