中国畜牧杂志2024，Vol.60Issue(6)：107-112,6.DOI:10.19556/j.0258-7033.20230927-03
38,XX-DSD(SRY-)间性猪分子病因学的研究进展
Advances in the Molecular Pathogenesis of Hermaphroditic Pigs(38,XX-DSD,SRY-)
摘要
Abstract
As a national strategic and foundational key industry,the swine breeding plays a crucial role to ensure the long-term and stable development in pig industry.Hermaphroditic pigs with an XX karyotype,suffering from Disorders of Sex Development(XX-DSD),were characterized by abnormal reproductive system development.They often hamper the efficient production of pig breeding and affect the economic benefits of pig farming.Construction the precise molecular diagnostic techniques for hermaphroditic pigs can ensure breeding optimization and genetic improvement,which can provide valuable animal models for disorders of sex development of human,and also contribute to the high-quality development of both agricultural and medical pig industries.The classification of XX-DSD in humans and other animal model,regulatory factors,and mutations in causative genes were reviewed in this study,especially demonstrated the classification,characteristics,heritability and molecular genetics in hermaphroditic pigs.All these will provide theoretical references for the genetic diagnosis of hermaphroditic pigs.关键词
间性猪/XX-DSD/遗传诊断Key words
Hermaphroditic pigs/XX-DSD/Genetic diagnosis分类
畜牧业引用本文复制引用
钟秉洲,吴金华,于聪颖,裴杨莉,冯政,李华..38,XX-DSD(SRY-)间性猪分子病因学的研究进展[J].中国畜牧杂志,2024,60(6):107-112,6.基金项目
国家自然科学基金项目(32072699) （32072699）
广东省粤佛联合基金重点项目(2020B1515120057) （2020B1515120057）
广东省重大研发项目(2022B0202090001) （2022B0202090001）
