中国药物评价2024，Vol.41Issue(2)：97-100,4.
HPLC法测定金丹附延颗粒中肉桂酸和桂皮醛的含量
Determination of Cinnamic Acid and Cinnamic Aldehyde in Jindan Fuyan Granules by HPLC
摘要
Abstract
Objective:To establish a HPLC method for the determination of cinnamic acid and cinnamic aldehyde in Jindan Fuyan granules.Methods:Cinnamic acid and cinnamic aldehyde were separated by C18 column with a mobile phase consisting of acetonitrile-0.1％phosphoric acid solution.The detection wavelength was set at 290 nm with a flow rate of 1.0 mL·min-1 and a chromatographic column temperature of 25 ℃.Results:Cinnamic acid and cinnamic aldehyde were present in the concentration range of 0.207 9-10.3938 μg·mL-1 and 0.202 5-10.127 0 μg·mL-1(r=1.000 0),and the recoveries were 100.3％and 102.6％,RSDs were 1.57％and 1.82％,respectively.Conclusion:The method is simple,stable,and can be used for the determination of cinnamic acid and cinnamic aldehyde in Jindan Fuyan granules.关键词
金丹附延颗粒/含量测定/肉桂酸/桂皮醛/高效液相色谱Key words
Jindan Fuyan granule/Content determination/Cinnamic acid/Cinnamic aldehyde/High Performance Liquid Chromatog-raphy(HPLC)分类
医药卫生引用本文复制引用
朱艳艳,刘德鸿,吴倩颖,朱良辉,陈伟康..HPLC法测定金丹附延颗粒中肉桂酸和桂皮醛的含量[J].中国药物评价,2024,41(2):97-100,4.基金项目
江西省药品监督管理局2023年重点项目(编号:2023JS11) （编号:2023JS11）
