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高变异药物等效性评估方法在Excel中的实现

唐韵 王杰 苏远 吴昭君 何鸽飞

中国药物评价2024,Vol.41Issue(2):124-127,4.
中国药物评价2024,Vol.41Issue(2):124-127,4.

高变异药物等效性评估方法在Excel中的实现

Evaluation of Bioequivalence for Highly Variable Drugs by Excel

唐韵 1王杰 1苏远 1吴昭君 1何鸽飞1

作者信息

  • 1. 长沙市第一医院药剂科,湖南 长沙 410013
  • 折叠

摘要

Abstract

Objective:A simple and efficient bioequivalence evaluation for highly variable drugs was established by Excel.Methods:The built-in statistical analysis function of Excel was used to perform statistical tests such as one-way ANOVA,90%confidence limit and upper 95%confidence limit based on the data.Results:The bioequivalence evaluation of highly variable drugs was conducted by Excel,and the within-subject variation,90%confidence limit and upper 95%confidence limit were consistent with the results of Phoenix Win-Nonlin.Conclusion:The bioequivalence evaluation for highly variable drugs can be realized in Excel,and the whole data processing process is efficient,fast and reliable,which is an ideal method to process the bioequivalenc data for highly variable drugs.

关键词

高变异药物/参比制剂校正平均生物等效性/生物等效性/单因素方差分析/Excel

Key words

Highly variable drugs/Reference-scaled average bioequivalence/Bioequivalence/One-Way ANOVA/Excel

分类

医药卫生

引用本文复制引用

唐韵,王杰,苏远,吴昭君,何鸽飞..高变异药物等效性评估方法在Excel中的实现[J].中国药物评价,2024,41(2):124-127,4.

中国药物评价

2095-3593

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