中国医学装备2024，Vol.21Issue(5)：79-82,87,5.DOI:10.3969/j.issn.1672-8270.2024.05.015
剪切波弹性成像检测尿道周围前列腺组织弹性模量与良性前列腺增生患者血清前列腺特异抗原的相关性研究
Correlation study of the elastic modulus of shear wave elastography of periurethral prostatic tissue and serum PSA in patients with benign prostatic hyperplasia
摘要
Abstract
Objective:To analyze the correlation between elastic modulus of shear wave elastography of periurethral prostatic tissue and serum prostate-specific antigen(PSA)in patients with benign prostatic hyperplasia(BPH).Methods:A total of 200 BPH patients who received treatment in the Second People's Hospital of Hefei from October 2019 to October 2022 were collected by convenient sampling method,and all patients were subjected to ultrasound shear wave elastography and serum PSA examination,and the elastic modulus of periurethral prostate tissue was measured by shear wave elastography,and the mean of them was obtained.They were divided into mild group(96 cases),moderate group(59 cases)and severe group(45 cases)according to the results of the International Prostate Symptom Score(IPSS).At the same time,the related information of 30 cases without prostatic lesions who were selected from the prostate examination population were included into healthy control groups.The correlation between the elastic modulus of periurethral prostatic tissue and serum PSA was analyzed and compared.Results:Statistical analysis showed that there was significant difference in the elastic modulus value of prostate among various groups(F=190.914,P<0.05).Compared with the healthy control group,the elastic modulus values of prostate of the mild,moderate and severe groups were significantly increased,and the differences were significant(t=6.572,14.172,18.441,P<0.05),respectively.Compared with the mild group,the elastic modulus values of prostate of the moderate and severe groups were significantly increased(t=7.853,18.274,P<0.05),respectively.Compared with the moderate group,the elasticity modulus value of prostate of the severe group significantly increased(t=11.371,P<0.05).There was significant difference in serum PSA among BPH patients with different degrees(F=126.143,P<0.05).Compared with the healthy control group,the serum PSA values of the mild,moderate and severe groups significantly increased(t=10.694,14.368,13.804,P<0.001),respectively.Compared with the mild group,the serum PSA values of the moderate and severe group significantly increased(t=6.401,13.047,P<0.05),respectively.Compared with the moderate group,the serum PSA value of the patients in the severe group significantly increased(t=7.293,P<0.001).There was no significant correlation between serum PSA and the elastic modulus of periurethral tissues in the healthy control group(P>0.05).There were significant positive correlation between serum PSA and the elastic modulus of periurethral tissues in the mild,moderate and severe groups(r=0.314,0.296,0.354,P<0.05),respectively.Conclusion:Both serum PSA level and elastic modulus value of periurethral prostate tissue of BPH patients significantly increase,and there is a positive correlation between them.关键词
良性前列腺增生(BPH)/前列腺特异抗原(PSA)/剪切波弹性成像/相关性分析Key words
Benign prostatic hyperplasia(BPH)/Prostate specific antigen/Shear wave elastography/Correlation analysis分类
医药卫生引用本文复制引用
杨振兴,魏灿,席俊华,齐伟,张艳斌..剪切波弹性成像检测尿道周围前列腺组织弹性模量与良性前列腺增生患者血清前列腺特异抗原的相关性研究[J].中国医学装备,2024,21(5):79-82,87,5.基金项目
国家自然科学基金(82004010) National Nature Science Foundation of China(82004010) （82004010）
