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基于内质网应激探讨慢性冠脉综合征从脾治心内涵

徐镕锌 王晗

中国中医药图书情报杂志2024,Vol.48Issue(4):19-23,5.
中国中医药图书情报杂志2024,Vol.48Issue(4):19-23,5.DOI:10.3969/j.issn.2095-5707.202401013

基于内质网应激探讨慢性冠脉综合征从脾治心内涵

Discussion on the Connotation of Treating the Heart from the Spleen in Chronic Coronary Syndrome Based on Endoplasmic Reticulum Stress

徐镕锌 1王晗1

作者信息

  • 1. 南京中医药大学附属医院,江苏 南京 210029
  • 折叠

摘要

Abstract

According to TCM,the heart and spleen are closely linked in physiology and pathology;spleen diseases can lead to heart diseases,and heart diseases can be cured from the spleen.Endoplasmic reticulum homeostasis and stress are similar to the physiology and pathology of the spleen,and may be a reflection of spleen function at the subcellular level.Endoplasmic reticulum stress is a pathogenic factor in chronic coronary syndromes,and promotes the progression of chronic coronary syndromes by participating in the formation of atherosclerosis and vascular endothelial dysfunction,which is similar to the process of spleen involvement in the formation of phlegm and blood stasis leading to chest obstruction.The connection between ERS and chronic coronary syndromes provides a reference for the treatment of the heart from the spleen and treating the heart and spleen together in TCM,and provides ideas for the prevention and treatment of chronic coronary syndromes in TCM.

关键词

内质网应激/慢性冠脉综合征/从脾治心

Key words

endoplasmic reticulum stress/chronic coronary syndrome/treating the heart from the spleen

分类

医药卫生

引用本文复制引用

徐镕锌,王晗..基于内质网应激探讨慢性冠脉综合征从脾治心内涵[J].中国中医药图书情报杂志,2024,48(4):19-23,5.

基金项目

江苏省卫生健康委科研课题(BJ20021) (BJ20021)

江苏省老年健康科研项目(LKZ2023002) (LKZ2023002)

中国中医药图书情报杂志

2095-5707

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