中山大学学报（医学科学版）2024，Vol.45Issue(3)：331-336,6.
NGF与TrkA受体在儿童膀胱过度活动症中的研究进展
Research Progress on NGF and TrkA Receptors in Pediatric Overactive Bladder
摘要
Abstract
Nerve growth factor(NGF)has been widely studied because it plays an important role in the survival,growth and differentiation of nerve cells.It is distributed throughout the body and plays different pathophysiological roles according to the combined receptors.TrkA is its high affinity receptor,and many studies have shown that NGF plays differ-ent roles according to its downstream signal transduction pathways after combining with it.After combining with NGF,it al-so has a cross-effect on other signal transduction pathways that occur in the body.This paper reviews the signal transduc-tion pathways combined with NGF and TrkA from different disease symptoms,so as to explore the role of NGF/TrkA signal pathways in children with overactive bladder.关键词
神经生长因子/儿童膀胱过度活动症/原肌球蛋白相关激酶A受体/低亲和力神经营养因子p75受体/信号转导通路Key words
nerve growth factor/pediatric overactive bladder/TrkA receptor/p75 receptor/signal transduction pathway分类
医药卫生引用本文复制引用
何萍,潮敏..NGF与TrkA受体在儿童膀胱过度活动症中的研究进展[J].中山大学学报（医学科学版）,2024,45(3):331-336,6.基金项目
安徽省科技厅临床医学研究转化专项项目(202304295107020066) （202304295107020066）
