中国现代医生2024，Vol.62Issue(14)：11-14,4.DOI:10.3969/j.issn.1673-9701.2024.14.003
2016至2020年杭州地区无偿献血人群HIV感染状况分析
Analysis on HIV infection status of unpaid blood donors in Hangzhou from 2016 to 2020
摘要
Abstract
Objective To understand the status of HIV infection among unpaid blood donors in Hangzhou,and to provide data support for reducing the risk of HIV transmission through blood transfusion,and formulating effective blood donor recruitment and AIDS prevention and control strategies in Hangzhou.Methods Enzyme-linked immunosorbent assay(ELISA)and nucleic acid testing(NAT)were used to detect HIV-I/Ⅱ antibody/antigen and HIV RNA from 902 847 unpaid blood donors in Hangzhou from January 2016 to December 2020.Anti-HIV antibody/antigen or HIV RNA reactive samples were sent to Hangzhou Center for Disease Control(CDC)for further confirmation by Western bloting and NAT.Results A total of 103 HIV positive cases were detected in Hangzhou area from January 2016 to December 2020,with a positive detection rate of 0.01%,101 cases were positive for ELISA and NAT screening,2 cases were negative for ELISA screening and positive for NAT.Among the 103 infected patients,males(91.26%,94/103),18-35 years old(69.90%,72/103),and first-time blood donors(68.93%,71/103)were the majority.The positive rate of HIV among blood donors decreased year by year from 2016 to 2020(χ2=7.181,P=0.007),but there was no significant difference in HIV positive rate between male and female blood donors(χ2=10.336,P=0.350;χ2=0.653,P=0.957).There was no significant difference in HIV positive rate among blood donors of different age groups(χ2=6.378,P=0.173;χ2=2.318,P=0.678;χ2=5.284,P=0.259;χ2=9.183,P=0.057).Conclusion In recent 5 years,HIV infection has been at a low epidemic level among unpaid blood donors in Hangzhou,but there is still an infection risk.It is necessary to strengthen the recruitment of blood donors from low-risk groups,adopt advanced detection technology and select appropriate detection strategies to ensure blood safety.关键词
献血者/HIV感染/酶联免疫吸附试验/核酸检测Key words
Blood donors/HIV infection/Enzyme linked immunosorbent assay/Nucleic acid testing分类
医药卫生引用本文复制引用
励晓涛,董杰,凌霞,祝宏,吴丹霄..2016至2020年杭州地区无偿献血人群HIV感染状况分析[J].中国现代医生,2024,62(14):11-14,4.基金项目
浙江省医药卫生科技计划项目(2019KY068) （2019KY068）
