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首页|期刊导航|Zoological Research|PCDH17 restricts dendritic spine morphogenesis by regulating ROCK2-dependent control of the actin cytoskeleton,modulating emotional behavior

PCDH17 restricts dendritic spine morphogenesis by regulating ROCK2-dependent control of the actin cytoskeleton,modulating emotional behavior

Laidong Yu Fangfang Zeng Mengshu Fan Kexuan Zhang Jingjing Duan Yalu Tan Panlin Liao Jin Wen Chenyu Wang Meilin Wang Jialong Yuan Xinxin Pang Yan Huang Yangzhou Zhang Jia-Da Li Zhuohua Zhang Zhonghua Hu

Zoological Research2024,Vol.45Issue(3):P.535-550,16.
Zoological Research2024,Vol.45Issue(3):P.535-550,16.DOI:10.24272/j.issn.2095-8137.2024.055

PCDH17 restricts dendritic spine morphogenesis by regulating ROCK2-dependent control of the actin cytoskeleton,modulating emotional behavior

Laidong Yu 1Fangfang Zeng 1Mengshu Fan 1Kexuan Zhang 1Jingjing Duan 2Yalu Tan 2Panlin Liao 2Jin Wen 1Chenyu Wang 3Meilin Wang 3Jialong Yuan 1Xinxin Pang 1Yan Huang 2Yangzhou Zhang 2Jia-Da Li 4Zhuohua Zhang 5Zhonghua Hu6

作者信息

  • 1. Hunan Key Laboratory of Molecular Precision Medicine,Department of Critical Care Medicine,Xiangya Hospital,Central South University,Changsha,Hunan 410008,China Center for Medical Genetics and Hunan Key Laboratory of Medical Genetics,School of Life Sciences,Central South University,Changsha,Hunan 410008,China
  • 2. Hunan Key Laboratory of Molecular Precision Medicine,Department of Critical Care Medicine,Xiangya Hospital,Central South University,Changsha,Hunan 410008,China National Clinical Research Center for Geriatric Disorders,Xiangya Hospital,Central South University,Changsha,Hunan 410008,China Hunan Provincial Clinical Research Center for Critical Care Medicine,Xiangya Hospital,Central South University,Changsha,Hunan 410008,China
  • 3. Hunan Key Laboratory of Molecular Precision Medicine,Department of Critical Care Medicine,Xiangya Hospital,Central South University,Changsha,Hunan 410008,China
  • 4. Center for Medical Genetics and Hunan Key Laboratory of Medical Genetics,School of Life Sciences,Central South University,Changsha,Hunan 410008,China Hunan Key Laboratory of Animal Models for Human Diseases,School of Life Sciences,Central South University,Changsha,Hunan 410008,China MOE Key Lab of Rare Pediatric Diseases,School of Life Sciences,Central South University,Changsha,Hunan 410008,China
  • 5. Hunan Key Laboratory of Molecular Precision Medicine,Department of Critical Care Medicine,Xiangya Hospital,Central South University,Changsha,Hunan 410008,China Center for Medical Genetics and Hunan Key Laboratory of Medical Genetics,School of Life Sciences,Central South University,Changsha,Hunan 410008,China MOE Key Lab of Rare Pediatric Diseases,School of Life Sciences,Central South University,Changsha,Hunan 410008,China Department of Neurosciences,University of South China Medical School,Hengyang,Hunan 421001,China
  • 6. Hunan Key Laboratory of Molecular Precision Medicine,Department of Critical Care Medicine,Xiangya Hospital,Central South University,Changsha,Hunan 410008,China Center for Medical Genetics and Hunan Key Laboratory of Medical Genetics,School of Life Sciences,Central South University,Changsha,Hunan 410008,China National Clinical Research Center for Geriatric Disorders,Xiangya Hospital,Central South University,Changsha,Hunan 410008,China Hunan Provincial Clinical Research Center for Critical Care Medicine,Xiangya Hospital,Central South University,Changsha,Hunan 410008,China MOE Key Lab of Rare Pediatric Diseases,School of Life Sciences,Central South University,Changsha,Hunan 410008,China
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摘要

关键词

Synapse development/Dendritic spine/Mood disorder/Actin cytoskeleton/Animal behavior

分类

医药卫生

引用本文复制引用

Laidong Yu,Fangfang Zeng,Mengshu Fan,Kexuan Zhang,Jingjing Duan,Yalu Tan,Panlin Liao,Jin Wen,Chenyu Wang,Meilin Wang,Jialong Yuan,Xinxin Pang,Yan Huang,Yangzhou Zhang,Jia-Da Li,Zhuohua Zhang,Zhonghua Hu..PCDH17 restricts dendritic spine morphogenesis by regulating ROCK2-dependent control of the actin cytoskeleton,modulating emotional behavior[J].Zoological Research,2024,45(3):P.535-550,16.

基金项目

supported by the National Natural Science Foundation of China(82171506 and 31872778) (82171506 and 31872778)

Discipline Innovative Engineering Plan(111 Program)of China(B13036) (111 Program)

Key Laboratory Grant from Hunan Province(2016TP1006) (2016TP1006)

Department of Science and Technology of Hunan Province(2021DK2001,Innovative Team Program 2019RS1010) (2021DK2001,Innovative Team Program 2019RS1010)

Innovation-Driven Team Project from Central South University(2020CX016) (2020CX016)

Hunan Hundred Talents Program for Young Outstanding Scientists。 ()

Zoological Research

OACSTPCD

2095-8137

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