1例生痰二氧化碳嗜纤维菌脑膜炎合并肾功能亢进患儿的抗感染治疗实践OACSTPCD

Objective:To probe into the role of clinical pharmacists in anti-infective treatment of bacterial meningitis in children.Methods:Clinical pharmacists participated into multiple pharmaceutical consultations for a child with Capnocytophaga sputigena bacteremia meningitis complicated with augmented renal clearance.Clinical pharmacists cooperated with clinicians to analyze the causes of poor therapeutic effects,and optimized the anti-infective treatment regimen and implemented pharmacological care in combination with the special physiopathological characteristics of augmented renal clearance and pharmacokinetics/pharmacodynamics(PK/PD)theory of antibiotics.Results:The treatment regimen proposed by clinical pharmacists was adopted by clinicians.The child was clinically stable with normal cerebrospinal fluid and was discharged successfully.Conclusion:Clinical pharmacists should give full play to the professional expertise in pharmacy to further improve the clinical efficacy of anti-infective drugs for special site infections induced by rare pathogenic bacteria in the clinic.