儿科药学杂志2024，Vol.30Issue(6)：37-41,5.DOI:10.13407/j.cnki.jpp.1672-108X.2024.06.010
硝酸甘油在早产儿外周组织缺血应用1例并文献复习
Application of Nitroglycerin in Peripheral Tissue Ischemia in Preterm Infants:a Case Report and Literature Review
林静兰 1林倩清 1黄咏欣 1何兰 1叶秀桢1
作者信息
摘要
Abstract
Objective:To summarize the application of nitroglycerin in neonatal peripheral tissue ischemia.Methods:Clinical data of a preterm infant with peripheral tissue ischemia treated with nitroglycerin in our hospital in Mar.2022 were retrospectively analyzed.CNKI,Wanfang and PubMed databases were retrieved to collect application data of nitroglycerin in neonates with peripheral tissue ischemia.Descriptive statistical analysis method was adopted.Results:Peripheral tissue ischemia occurred in the punctured limb after peripheral central venous catheter(PICC)insertion for 1 h,and was successfully cured by nitroglycerin after routine treatment for 8 h without improvement.The median time of first administration of nitroglycerin in 48 neonates(1 case in this study and 47 cases in reported literature)with peripheral tissue ischemia was 3(0,192)h after peripheral tissue ischemia and 2(0.02,32)d after treatment.Totally 79.2％(38/48)recovered completely,20.8％(10/48)had tissue necrosis,95.8％(46/48)were discharged successfully,and 4.2％(2/48)died during follow-up treatment.Conclusion:Nitroglycerin has significant efficacy and safety profile in the treatment of peripheral tissue ischemia in neonates with early application.关键词
硝酸甘油/早产儿/组织/缺血Key words
nitroglycerin/preterm infants/tissue/ischemia分类
医药卫生引用本文复制引用
林静兰,林倩清,黄咏欣,何兰,叶秀桢..硝酸甘油在早产儿外周组织缺血应用1例并文献复习[J].儿科药学杂志,2024,30(6):37-41,5.
