广东医学2024，Vol.45Issue(5)：571-576,6.DOI:10.13820/j.cnki.gdyx.20231894
细菌感染患者发生脓毒症的临床特点及危险因素分析
Clinical characteristics and risk factors analysis of septic patients with bacterial infections
摘要
Abstract
Objective To analyze the clinical characteristics and risk factors of septic patients with bacterial in-fections.Methods A total of 2 158 patients with positive bacterial cultures from October 1,2019,to September 30,2020,were collected,including 229 cases in the septic group and 1 929 cases in the non-septic group.General informa-tion,laboratory test results,medical history of underlying diseases,and clinical manifestations were collected and com-pared between the two groups.Relevant risk factors were screened using T-test or approximate T-test for continuous variables,Pearson chi-square test,Fisher's exact test for categorical variables,and non-conditional logistic regression model.Results Compared with the non-septic group,there were statistically significant differences in gender,age,smoking,alcohol consumption,congestive heart failure,chronic kidney disease(CKD),chronic hepatitis B,liver cirrho-sis,and malignant tumors(all P＜0.05).Male gender(OR=2.17,P＜0.01),age(OR=1.01,P＜0.05),and chronic hepatitis B(OR=1.86,P＜0.05)were identified as independent risk factors for sepsis.Conclusion Sepsis was significantly associated with male gender,older age,smoking,and alcohol consumption.Patients with congestive heart failure,CKD,chronic hepatitis B,liver cirrhosis,and malignant tumors were more likely to develop sepsis.Male gender,older age,and chronic hepatitis B were independent risk factors for sepsis.关键词
细菌感染/脓毒症/危险因素Key words
bacterial infection/sepsis/risk factors分类
医药卫生引用本文复制引用
黄迪希,欧阳慧,罗玉婷,纪宇欣,刘曦..细菌感染患者发生脓毒症的临床特点及危险因素分析[J].广东医学,2024,45(5):571-576,6.基金项目
国家自然科学基金青年项目(82101843) （82101843）
