临床小儿外科杂志2024，Vol.23Issue(5)：496-500,5.DOI:10.3760/cma.j.cn101785-202302029-020
先天性肛门直肠畸形病因学研究进展
Research advances in etiology of congenital anorectal malformations
摘要
Abstract
Anorectal malformation(ARM)is the most common congenital gastrointestinal malformation in children.It has a low prenatal diagnostic rate.The major treatments include posterior sagittal anoplasty and laparoscopic-assisted anoplasty.Most children develop postoperative complications.Understanding its etiology is helpful to prevent its occurrence and develop more appropriate treatments.Domestic and foreign scholars believe that the occurrence of ARM may be related to chromosomal abnormalities,syndrome associated factors,environ-mental factors and some unfavorable prenatal habits and maternal factors.Since its specific etiology has re-mained elusive,this review was intended to elucidate the pathogenesis of ARM from genetic and non-genetic factors and focused upon the pathogenesis of ARM and related signaling pathways and genes.关键词
肛门直肠畸形/外科手术/儿童Key words
Anorectal Malformations/Surgical Procedures,Operative/Child引用本文复制引用
张博,侯亚如,康雪莲,董娟,李勇..先天性肛门直肠畸形病因学研究进展[J].临床小儿外科杂志,2024,23(5):496-500,5.基金项目
甘肃省哲学社会科学规划项目(SH036) Gansu Provincial Philosophy and Social Sciences Planning Project(SH036) （SH036）
