中国比较医学杂志2024，Vol.34Issue(4)：147-155,9.DOI:10.3969/j.issn.1671-7856.2024.04.018
慢性应激实验动物模型的应用与展望
Application and research prospects of experimental animal models of chronic stress
摘要
Abstract
The effect and mechanism of chronic stress on psychosomatic diseases are important topics in stress research.The establishment of animal models to simulate human chronic stress is of great significance to investigations of stress responses,the pathogenesis of related diseases,clinical treatment,and drug development.In this paper,animal models of chronic stress commonly used in China and abroad are reviewed;the classification of stressors,animal selection,model construction,pathological manifestations,and evaluation indexes are summarized;and the advantages and disadvantages and application of various models are discussed.The paper provides a reference for the study and selection of models of chronic stress response.关键词
慢性应激/动物模型/评价指标Key words
chronic stress/animal model/evaluation indices分类
医药卫生引用本文复制引用
岳小琪,李玉婷,姜淼,赵自刚,牛春雨..慢性应激实验动物模型的应用与展望[J].中国比较医学杂志,2024,34(4):147-155,9.基金项目
国家自然科学基金面上项目(82270524) （82270524）
河北省硕士在读研究生创新能力培养资助项目(CXZZSS2024128). （CXZZSS2024128）
