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外周血白细胞分类计数及其比例在甲型流感病毒感染患者中的临床意义

纪国文 卫雨清 刘宏炜 潘天宇 段晶晶

中国医学创新2024,Vol.21Issue(15):89-93,5.
中国医学创新2024,Vol.21Issue(15):89-93,5.DOI:10.3969/j.issn.1674-4985.2024.15.021

外周血白细胞分类计数及其比例在甲型流感病毒感染患者中的临床意义

Clinical Significance of Peripheral Blood Leukocyte Classification Counts and Their Proportions in Patients with Influenza A Virus Infection

纪国文 1卫雨清 2刘宏炜 1潘天宇 1段晶晶3

作者信息

  • 1. 上海市奉贤区中心医院呼吸内科 上海 201499
  • 2. 上海市奉贤区奉浦街道社区卫生服务中心全科 上海 201401
  • 3. 上海市奉贤区中心医院药剂科 上海 201499
  • 折叠

摘要

Abstract

Objective:To explore the application value of peripheral blood leukocyte classification counts and their proportions in patients with influenza A virus infection.Method:A total of 153 patients with respiratory and related systemic symptoms who were admitted to the Fever Clinic of Fengpu Street Community Health Service Center,Fengxian District,Shanghai from March to April 2023 were retrospective collected,according to the results of rapid antigen test of influenza A virus,they were divided into 71 cases of influenza A group and 82 cases of non influenza A group.The patient's sex,age,maximum body temperature,white blood cell count(WBC),neutrophil count(NC),lymphocyte count(LC),monocyte count(MC),eosinophil count(EOS)and neutrophil percentage(NE%),lymphocyte percentage(LY%),monocyte percentage(MO%),eosinophil percentage(EOS%)were recorded.The diagnostic efficacy of leukocyte classification counts and its proportion for influenza A virus infection was evaluated by the receiver operating characteristics(ROC)curve.Result:WBC,NC,LC,EOS and EOS%in the influenza A group were lower than those in the non influenza A group(P<0.05);and the highest body temperature and MO%were higher than those in the non influenza A group(P<0.05).The ROC analysis results showed that the area under the curve for MO%to diagnose influenza A virus infection was 0.704,the optimal critical point was 9.35%,and the sensitivity and specificity were 77.5%and 65.9%,respectively.Conclusion:The peripheral blood WBC,NC,LC,EOS and EOS%of patients infected with influenza A virus decrease,while the MO%increase,which has good auxiliary diagnostic value for influenza A virus infection.

关键词

甲型流感病毒/白细胞计数/单核细胞计数比例

Key words

Influenza A virus/White blood cell count/Monocyte count proportion

引用本文复制引用

纪国文,卫雨清,刘宏炜,潘天宇,段晶晶..外周血白细胞分类计数及其比例在甲型流感病毒感染患者中的临床意义[J].中国医学创新,2024,21(15):89-93,5.

基金项目

上海市奉贤区科委项目(奉科20201616) (奉科20201616)

中国医学创新

1674-4985

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