Reconstitution of double-negative T cells after cord blood transplantation and its predictive value for acute graft-versus-host diseaseOACSTPCDMEDLINE

作者：Tianzhong Pan;Dongyao Wang;Xiaoyu Zhu;Peng Ding;Aijie Huang;Baolin Tang;Kaidi Song;Guangyu Sun;Yue Wu;Shiying Yang;Xingchi Chen

作者单位：Department of Hematology,The First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei,Anhui 230001,China||Anhui Provincial Key Laboratory of Blood Research and Applications,Hefei,Anhui,230001,China||Blood and Cell Therapy Institute,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei,Anhui 230001,ChinaThe First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei,Anhui 230001,ChinaDepartment of Hematology,The First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei,Anhui 230001,China||Anhui Provincial Key Laboratory of Blood Research and Applications,Hefei,Anhui,230001,China||Blood and Cell Therapy Institute,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei,Anhui 230001,ChinaDivision of Life Sciences and Medicine,University of Science and Technology of China,Hefei,Anhui 230001,ChinaThe First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei,Anhui 230001,ChinaDepartment of Hematology,The First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei,Anhui 230001,China||Anhui Provincial Key Laboratory of Blood Research and Applications,Hefei,Anhui,230001,China||Blood and Cell Therapy Institute,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei,Anhui 230001,ChinaDepartment of Hematology,The First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei,Anhui 230001,ChinaDepartment of Hematology,The First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei,Anhui 230001,China||Anhui Provincial Key Laboratory of Blood Research and Applications,Hefei,Anhui,230001,China||Blood and Cell Therapy Institute,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei,Anhui 230001,ChinaDepartment of Hematology,The First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei,Anhui 230001,China||Anhui Provincial Key Laboratory of Blood Research and Applications,Hefei,Anhui,230001,China||Blood and Cell Therapy Institute,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei,Anhui 230001,ChinaDepartment of Hematology,The First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei,Anhui 230001,China||Anhui Provincial Key Laboratory of Blood Research and Applications,Hefei,Anhui,230001,China||Blood and Cell Therapy Institute,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei,Anhui 230001,ChinaDepartment of Hematology,The First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei,Anhui 230001,China||Anhui Provincial Key Laboratory of Blood Research and Applications,Hefei,Anhui,230001,China||Blood and Cell Therapy Institute,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei,Anhui 230001,China

中文关键词：Umbilical cord blood transplantationGraft-versus-host diseaseImmune reconstitutionDouble negative THema-tological MalignanciesTreg cellBreg cell

英文关键词：Umbilical cord blood transplantationGraft-versus-host diseaseImmune reconstitutionDouble negative THema-tological MalignanciesTreg cellBreg cell

刊名：《中华医学杂志（英文版）》 2024 (10)

页码/页数：1207-1217,11

基金：This work was supported by grants from the National Natural Science Foundation of China(Nos.82270223,82170209,and 82100230),the Anhui Provincial Key Research and Development Project(No.2022e07020015),the Anhui Health Research Project(No.AHWJ2022a011),and the Fundamental Research Funds for the Central Universities(Nos.WK9110000204,and WK9110000168).

DOI：10.1097/CM9.0000000000002807