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Impacts of PI3K/protein kinase B pathway activation in reactive astrocytes: from detrimental effects to protective functions

Ramón Pérez-Núñez María Fernanda González Ana María Avalos Lisette Leyton

Neural Regeneration Research2025，Vol.20Issue(4)：P.1031-1041,11.

Neural Regeneration Research2025，Vol.20Issue(4)：P.1031-1041,11.DOI:10.4103/NRR.NRR-D-23-01756

Impacts of PI3K/protein kinase B pathway activation in reactive astrocytes: from detrimental effects to protective functions

Ramón Pérez-Núñez ¹María Fernanda González ¹Ana María Avalos ²Lisette Leyton¹

作者信息

1. Cellular Communication Laboratory,Programa de Biología Celular y Molecular,Center for Studies on Exercise,Metabolism and Cancer(CEMC),Instituto de Ciencias Biomédicas(ICBM),Facultad de Medicina,Universidad de Chile,Santiago,Chile Advanced Center for Chronic Diseases(ACCDiS),Faculty of Chemical and Pharmaceutical Sciences&Faculty of Medicine,Universidad de Chile,Santiago,Chile
2. Instituto de Ciencias Biomédicas,Facultad de Ciencias de la Salud,Universidad Autónoma de Chile,Santiago,Chile
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摘要

关键词

inflammation/integrins/neuroprotective/neurotoxic/phosphatidylinositol 3-kinase/reactive astrocytes/signal transduction/Thy-1(CD90)

分类

医药卫生

引用本文复制引用

Ramón Pérez-Núñez,María Fernanda González,Ana María Avalos,Lisette Leyton..Impacts of PI3K/protein kinase B pathway activation in reactive astrocytes: from detrimental effects to protective functions[J].Neural Regeneration Research,2025,20(4):P.1031-1041,11.

基金项目

supported by Fondo Nacional de Desarrollo Científico y Tecnológico(FONDECYT)#1200836,#1210644,and#1240888,and Agencia Nacional de Investigación y Desarrollo(ANID)-FONDAP#15130011(to LL) （FONDECYT）

FONDECYT#3230227(to MFG). （to MFG）

Neural Regeneration Research

ISSN：1673-5374

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