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轻质可排阻磁性分子印迹聚合物的制备及选择性分离和检测牛奶中痕量四环素

张军杰 王悦 吴秋含 沈如泉 刘涵 段新华

大学化学2024,Vol.39Issue(5):251-257,7.
大学化学2024,Vol.39Issue(5):251-257,7.DOI:10.3866/PKU.DXHX202311084

轻质可排阻磁性分子印迹聚合物的制备及选择性分离和检测牛奶中痕量四环素

Preparation and Selective Separation of Lightweight Magnetic Molecularly Imprinted Polymers for Trace Tetracycline Detection in Milk

张军杰 1王悦 1吴秋含 1沈如泉 1刘涵 1段新华1

作者信息

  • 1. 西安交通大学化学学院,西安 710049
  • 折叠

摘要

Abstract

This experiment addresses the pressing issue of milk safety,integrating cutting-edge molecular imprinting technology into undergraduate laboratory classes.A comprehensive experiment is designed,combining molecular imprinting,protein exclusion,and magnetic separation techniques to synthesize lightweight magnetic molecularly imprinted polymers.The polymers'performance is evaluated,and they are utilized as solid-phase extraction adsorbents in conjunction with high-performance liquid chromatography to establish a novel method for the direct and selective detection of trace tetracycline in milk samples.This interdisciplinary study spans materials chemistry,analytical chemistry,instrumental chemistry,and food chemistry,fostering students'scientific literacy,problem-solving abilities,and innovative thinking.The innovative design of the imprinting material and magnetic separation process ensures cost-effectiveness,ease of operation,and high safety throughout the experiment.Through this hands-on experience,students gain insight into molecular imprinting technology,learn new detection methods,refine basic laboratory skills,enhance data collection and analysis capabilities,and deepen their understanding of the interplay between components,performance,and application.

关键词

分子印迹聚合物/牛奶/四环素/综合化学实验

Key words

Molecularly imprinted polymer/Milk/Tetracycline/Comprehensive chemistry experiment

分类

社会科学

引用本文复制引用

张军杰,王悦,吴秋含,沈如泉,刘涵,段新华..轻质可排阻磁性分子印迹聚合物的制备及选择性分离和检测牛奶中痕量四环素[J].大学化学,2024,39(5):251-257,7.

基金项目

2022年西安交通大学本科教学改革研究项目(2203Z) (2203Z)

大学化学

1000-8438

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