大学化学2024，Vol.39Issue(5)：63-69,7.DOI:10.3866/PKU.DXHX202309098
红光诱导菠菜叶提取物催化对羟基苯甲腈的绿色合成
Green Synthesis of p-Hydroxybenzonitrile Catalyzed by Spinach Extracts under Red-Light Irradiation:Research and Exploration of Innovative Experiments for Pharmacy Undergraduates
摘要
Abstract
Visible light irradiation is a crucial factor in modern synthetic organic chemistry,yet it is often overlooked in undergraduate organic experiment textbooks.This innovative experiment introduces a microscale approach,inspired by the principles of photosynthesis,to catalyze the oxidation of p-cyanophenylboronic acid to p-hydroxybenzonitrile using extracts from spinach leaves under red-light irradiation.The incorporation of this comprehensive experiment into our school's organic chemistry laboratory teaching offers several advantages:(1)The environmentally friendly catalyst is easily accessible,and the synthesis process is safe and reliable with low experimental costs.(2)Microscale experiments contribute to reducing environmental pollution,enhancing laboratory safety,saving reagents and time,minimizing instrument wear and tear,and fostering students'meticulous experimental style and habits.(3)Beyond expanding students'knowledge and horizons,this experiment also ignites their interest in learning and boosts their learning enthusiasm.关键词
菠菜叶/叶绿素/红光/对羟基苯甲腈/绿色合成Key words
Spinach leaves/Chlorophyll/Red light/p-Hydroxybenzonitrile/Green synthesis分类
社会科学引用本文复制引用
曹陶,房方,李念光,张毅楠,詹其琛..红光诱导菠菜叶提取物催化对羟基苯甲腈的绿色合成[J].大学化学,2024,39(5):63-69,7.基金项目
2021年度南京中医药大学药学院课程思政示范项目(2021KCSZ008) （2021KCSZ008）
2022年度南京中医药大学本科教育教学改革研究课题重点项目(NZYJG2022012) （NZYJG2022012）
江苏高校品牌专业建设工程资助项目(PPZY2015A070) （PPZY2015A070）
