临床与病理杂志2024，Vol.44Issue(3)：474-482,9.DOI:10.11817/j.issn.2095-6959.2024.230673
慢性阻塞性肺疾病合并肺肉瘤样癌1例并文献复习
Chronic obstructive pulmonary disease complicated with pulmonary sarcomatoid carcinoma:A case report and literature review
摘要
Abstract
A retrospective analysis was conducted on the clinical manifestations,imaging features,pathological characteristics,treatment,and prognosis of an elderly patient with chronic obstructive pulmonary disease(COPD)complicated with pulmonary sarcomatoid carcinoma.Relevant literature was reviewed to enhance clinical understanding of such cases and to strengthen the standardized management of COPD complications.The patient,a 77-year-old male,presented with a soft tissue mass in the anterior segment of the right upper lobe,multiple nodules in both lungs,and lymphadenopathy on chest computed tomography(CT)scan.Percutaneous biopsy of the right lung confirmed sarcomatoid carcinoma,and genetic testing showed a mesenchymal-epithelial transition factor(MET)exon 14 skipping mutation.The patient received standard COPD management combined with the targeted drug Savolitinib,with a total survival time of 9 months.Lung cancer,as a severe complication of COPD,significantly affects the prognosis of COPD patients.Therefore,during standardized management of COPD,regular chest CT screening is essential for early detection,diagnosis,and treatment to improve prognosis and extend survival in COPD patients.关键词
慢性阻塞性肺疾病/肺肉瘤样癌/并发症Key words
chronic obstructive pulmonary disease/pulmonary sarcomatoid carcinoma/complications引用本文复制引用
朱志帆,刘虎,马克静,郝斌威,刘先胜,王锐英..慢性阻塞性肺疾病合并肺肉瘤样癌1例并文献复习[J].临床与病理杂志,2024,44(3):474-482,9.基金项目
山西省基础研究计划项目(202303021221194).This work was supported by the Fundamental Research Program of Shanxi Province,China(202303021221194). （202303021221194）
