慢性阻塞性肺疾病合并肺肉瘤样癌1例并文献复习OACSTPCD

A retrospective analysis was conducted on the clinical manifestations,imaging features,pathological characteristics,treatment,and prognosis of an elderly patient with chronic obstructive pulmonary disease(COPD)complicated with pulmonary sarcomatoid carcinoma.Relevant literature was reviewed to enhance clinical understanding of such cases and to strengthen the standardized management of COPD complications.The patient,a 77-year-old male,presented with a soft tissue mass in the anterior segment of the right upper lobe,multiple nodules in both lungs,and lymphadenopathy on chest computed tomography(CT)scan.Percutaneous biopsy of the right lung confirmed sarcomatoid carcinoma,and genetic testing showed a mesenchymal-epithelial transition factor(MET)exon 14 skipping mutation.The patient received standard COPD management combined with the targeted drug Savolitinib,with a total survival time of 9 months.Lung cancer,as a severe complication of COPD,significantly affects the prognosis of COPD patients.Therefore,during standardized management of COPD,regular chest CT screening is essential for early detection,diagnosis,and treatment to improve prognosis and extend survival in COPD patients.