摘要
Abstract
Objective To explore the clinical value of ultrasonic blood flow parameters combined with CT in the differential diagnosis of benign and ma-lignant breast nodules.Methods A total of 79 patients with breast nodules admitted to the Fuyang Fifth People's Hospital from January 2021 to Jan-uary 2023 were selected.All patients were confirmed by pathological diagnosis,including 42 cases of malignant nodules and 37 cases of benign nod-ules.All patients underwent ultrasound and CT examinations.The ultrasonic blood flow parameters(peak systolic velocity[PSV],resistance index[RI],and pulsatility index[PI])of patients in the benign nodule group were compared with those in the malignant nodule group.The CT morpholog-ical features and CT parameters(permeability surface[PS],blood flow[BF],and blood volume[BV])of patients in the benign nodule group were compared with those in the malignant nodule group.The changes in ultrasonic blood flow parameters and CT parameters in malignant nodules with different pathological features were compared.ROC curve analysis was used to evaluate the diagnostic value of ultrasonic blood flow parameters com-bined with CT parameters in the diagnosis of malignant breast nodules.Results The PSV,RI,and PI of patients in the malignant nodule group were sig-nificantly higher than those in the benign nodule group(P＜0.05).The non-uniform enhancement,spiculation,and lobulation rates of patients in the malignant nodule group were significantly higher than those in the benign nodule group(P＜0.05).The PS,BF,and BV of patients in the malignant nodule group were significantly higher than those in the benign nodule group(P＜0.05).The PSV,RI,and PI of patients in stage Ⅲ-Ⅳ malignant nodules were higher than those in stage Ⅰ-Ⅱ malignant nodules;the PSV,RI,and PI of poorly differentiated patients were higher than those of moderately to highly differentiated pa-tients;and the PSV,RI,and PI of patients with lymph node metastasis were higher than those without lymph node metastasis,all with statistical significance(P＜0.05).In malignant nodules,the PS,BF,and BV of patients in stage Ⅲ-Ⅳ were higher than those in stage Ⅰ-Ⅱ;the PS,BF,and BV of poorly differ-entiated patients were higher than those of moderately to highly differentiated patients;and the PS,BF,and BV of patients with lymph node metastasis were higher than those without lymph node metastasis,all with statistical significance(P＜0.05).ROC curve analysis showed that the sensitivity and specificity of ultrasonic blood flow parameters combined with CT parameters in the diagnosis of malignant nodules were significantly higher than those of ultrasonic blood flow parameters or CT parameters alone(P＜0.05).Conclusion Ultrasonic blood flow parameters combined with CT have good value in the differential diagnosis of benign and malignant breast nodules and can strengthen the sensitivity and specificity of diagnosing malignant nodules,suggesting clinical reference value.关键词
超声血流参数/CT/乳腺良恶性结节Key words
Ultrasonic blood flow parameters/CT/Benign and malignant breast nodules分类
医药卫生
