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转甲状腺素蛋白心脏淀粉样变的诊断与治疗研究进展

汪月 张俊峰

实用心电学杂志2024,Vol.33Issue(3):225-231,7.
实用心电学杂志2024,Vol.33Issue(3):225-231,7.DOI:10.13308/j.issn.2095-9354.2024.03.002

转甲状腺素蛋白心脏淀粉样变的诊断与治疗研究进展

Research advances in diagnosis and treatment of transthyretin cardiac amyloidosis

汪月 1张俊峰1

作者信息

  • 1. 200011 上海,上海交通大学医学院附属第九人民医院心内科
  • 折叠

摘要

Abstract

Transthyretin cardiac amyloidosis(ATTR-CA)has been considered as a rare cardiac dysfunction with occult onset,rapid progression and high mortality,caused by the accumulation of transthyretin fibrils in the myocardium.Recently,with the development of diagnostic techniques,its detection rate has been increasing.The continuous emergence of various small molecule drugs has also changed the previous situation of lacking therapeutic agents,and its mortality has been reduced.This paper mainly summarizes the latest advances in the diagnosis and treatment of ATTR-CA in recent years.

关键词

淀粉样变/心肌病/转甲状腺素/转甲状腺素蛋白心脏淀粉样变/心脏磁共振/小分子药物

Key words

amyloidosis/cardiomyopathy/transthyretin/transthyretin cardiac amyloidosis/cardiac magnetic resonance/small molecule drug

分类

医药卫生

引用本文复制引用

汪月,张俊峰..转甲状腺素蛋白心脏淀粉样变的诊断与治疗研究进展[J].实用心电学杂志,2024,33(3):225-231,7.

基金项目

九院临床研究助力计划资助项目(JYLJ202014) (JYLJ202014)

实用心电学杂志

2095-9354

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