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SORBS2对心肌病的影响及机制研究进展

韦天鹏 钱玲玲 王如兴

实用心电学杂志2024,Vol.33Issue(3):306-311,6.
实用心电学杂志2024,Vol.33Issue(3):306-311,6.DOI:10.13308/j.issn.2095-9354.2024.03.017

SORBS2对心肌病的影响及机制研究进展

Research advances in influence of SORBS2 on cardiomyopathy and its mechanism

韦天鹏 1钱玲玲 1王如兴1

作者信息

  • 1. 214023 江苏 无锡,南京医科大学附属无锡人民医院心内科
  • 折叠

摘要

Abstract

SORBS2 is a member of the SORBS adaptor protein family,and is highly expressed in the heart.SORBS2 is involved in the physiological processes such as cytoskeleton formation,cell adhesion and signal transduction.In recent years,more and more studies have shown that SORBS2 plays an important role in regulating the occurrence and development of cardiovascular diseases.Based on summarizing the protein structure and location of SORBS2,this paper reviews the role and mechanism of SORBS2 in the occurrence and development of myocardiopathies including left ventricular non-compaction cardiomyopathy and septic cardiomyopathy,in order to provide new ideas for the prevention and treatment of related myocardiopathies.

关键词

SORBS2/左室致密化不全性心肌病/脓毒症心肌病/扩张型心肌病/致心律失常性心肌病

Key words

SORBS2/left ventricular non-compaction cardiomyopathy/septic cardiomyopathy/dilated cardiomyopathy/arrhythmogenic cardiomyopathy

分类

医药卫生

引用本文复制引用

韦天鹏,钱玲玲,王如兴..SORBS2对心肌病的影响及机制研究进展[J].实用心电学杂志,2024,33(3):306-311,6.

基金项目

国家自然科学基金面上项目(82370342) (82370342)

无锡市"双百"医疗卫生中青年拔尖人才项目(BJ2023005) (BJ2023005)

实用心电学杂志

2095-9354

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