实用心电学杂志2024，Vol.33Issue(3)：316-319,4.DOI:10.13308/j.issn.2095-9354.2024.03.019
鸢尾素在急性心肌梗死中的保护作用研究进展
Research progress of protective effect of irisin in acute myocardial infarction
摘要
Abstract
Irisin is a hormone-like polypeptide secreted by the muscle tissue,which is generated after hydrolysis of fibronectin type Ⅲ domain-containing protein 5 by proteolytic enzymes,and released into the peripheral circulation.Irisin plays a potentially protective role in acute myocardial infarction(AMI).This article summarizes the present research progress of the protective effects of irisin in AMI mainly from the following aspects:reducing oxidative stress response,improving mitochondrial function,inhibiting myocardial apoptosis,inhibiting inflammatory response,improving microcirculation,in order to provide valuable references for the diagnosis and treatment of AMI.关键词
鸢尾素/急性心肌梗死/氧化应激/线粒体损伤/细胞凋亡Key words
irisin/acute myocardial infarction/oxidative stress/mitochondrial damage/apoptosis分类
医药卫生引用本文复制引用
王洋洋,谷云飞,李松森,王皓..鸢尾素在急性心肌梗死中的保护作用研究进展[J].实用心电学杂志,2024,33(3):316-319,4.基金项目
河南省自然科学基金资助项目(232300420247) （232300420247）
河南省科技攻关项目(212102310810) （212102310810）
