临床神经病学杂志2024，Vol.37Issue(3)：217-221,5.
基于特定靶点的重复经颅磁刺激在轻度认知功能障碍的应用及其脑网络基础
Application of target-specific repeated transcranial magnetic stimulation in mild cognitive impairment and relevant brain network basis
摘要
Abstract
Mild cognitive impairment(MCI)is an intermediate state between normal aging and dementia,and there is a risk of conversion to dementia if left untreated.Repetitive transcranial magnetic stimulation(rTMS)is a physical treatment for neuropsychiatric disorders that noninvasively acts on target area to upregulate neurotrophic substance expression,modulate cortical physiological activity,affect regional connectivity,and induce synaptic plasticity.On this basis,rTMS can realize targeted-regulation of damaged neural circuits,thereby improving cognitive dysfunction and becoming an effective method to intervene in MCI.This paper summarizes the theoretical background of this technology and further discusses the brain network that may be affected by target-specific rTMS in ameliorating MCI,in order to provide reference for clinical translation.关键词
轻度认知功能障碍/重复经颅磁刺激/大脑网络Key words
mild cognitive impairment/repetitive transcranial magnetic stimulation/brain network分类
医药卫生引用本文复制引用
毛芮,杨志远,徐运,柏峰..基于特定靶点的重复经颅磁刺激在轻度认知功能障碍的应用及其脑网络基础[J].临床神经病学杂志,2024,37(3):217-221,5.基金项目
国家自然科学基金项目(82071186) （82071186）
