临床医学工程2024，Vol.31Issue(6)：695-696,2.DOI:10.3969/j.issn.1674-4659.2024.06.0695
培氟沙星与盐酸米诺环素联合治疗慢性牙周炎的临床效果及对患者牙周炎性反应的影响
Clinical Effect of Pefloxacin Combined with Minocycline Hydrochloride in the Treatment of Chronic Periodontitis and Its Impact on Periodontal Inflammatory Reaction of Patients
李文萍 1陈萌萌1
作者信息
- 1. 南阳市口腔医院口腔黏膜病科,河南南阳 473000
- 折叠
摘要
Abstract
Objective To analyze the effect of pefloxacin combined with minocycline hydrochloride in the treatment of chronic periodontitis(CP).Methods 86 patients with CP were randomly divided into two groups.The control group was treated with minocycline hydrochloride,and the observation group was treated with pefloxacin on the basis of the control group.The clinical efficacy,periodontal inflammatory reaction and periodontal health status were compared between the two groups.Results After treatment,the total effective rate of the observation group was higher than that of the control group,and the levels of TNF-α,hs-CRP and IL-1β,and SBI,PLI,GI and PD were lower than those of the control group(P＜0.05).Conclusions Pefloxacin combined with minocycline hydrochloride can improve the therapeutic effect of CP,reduce periodontal inflammation reaction and improve periodontal health degree.关键词
慢性牙周炎/培氟沙星/盐酸米诺环素/牙周炎性反应Key words
Chronic periodontitis/Pefloxacin/Minocycline hydrochloride/Periodontal inflammatory reaction分类
医药卫生引用本文复制引用
李文萍,陈萌萌..培氟沙星与盐酸米诺环素联合治疗慢性牙周炎的临床效果及对患者牙周炎性反应的影响[J].临床医学工程,2024,31(6):695-696,2.
