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丙戊酸钠联合拉莫三嗪治疗癫痫的效果及对患者脑电图的影响

赵耀 王婷 杨荣成

临床医学工程2024,Vol.31Issue(6):657-658,2.
临床医学工程2024,Vol.31Issue(6):657-658,2.DOI:10.3969/j.issn.1674-4659.2024.06.0657

丙戊酸钠联合拉莫三嗪治疗癫痫的效果及对患者脑电图的影响

Effect of Sodium Valproate Combined with Lamotrigine in the Treatment of Epilepsy and Its Impact on EEG of Patients

赵耀 1王婷 1杨荣成1

作者信息

  • 1. 南阳医学高等专科学校第一附属医院神经内科,河南南阳 473000
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摘要

Abstract

Objective To explore the effect of sodium valproate combined with lamotrigine in the treatment of epilepsy.Methods 90 patients with epilepsy were randomly divided into two groups.The control group was treated with sodium valproate,and the study group was treated with sodium valproate combined with lamotrigine.The efficacy,EEG frequency and adverse reaction were compared between the two groups.Results After treatment,the total effective rate of the study group was higher than that of the control group,the frequencies of δand θ were lower than those of the control group,and the frequencies of α and β were higher than those of the control group(P<0.05).No significant difference was found in the incidence of adverse reactions between the two groups(P>0.05).Conclusions Sodium valproate combined with lamotrigine in the treatment of epilepsy has significant effect and high safety,and can improve the EEG frequency of patients.

关键词

丙戊酸钠/拉莫三嗪/癫痫/临床疗效/脑电图/不良反应

Key words

Sodium valproate/Lamotrigine/Epilepsy/Clinical efficacy/EEG/Adverse reaction

分类

医药卫生

引用本文复制引用

赵耀,王婷,杨荣成..丙戊酸钠联合拉莫三嗪治疗癫痫的效果及对患者脑电图的影响[J].临床医学工程,2024,31(6):657-658,2.

临床医学工程

1674-4659

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