临床医学工程2024，Vol.31Issue(6)：663-664,2.DOI:10.3969/j.issn.1674-4659.2024.06.0663
QCT骨密度测定对应用SGLT-2抑制剂的老年糖尿病患者骨质疏松和预后的评估
QCT Bone Mineral Density Measurement in Evaluation of Osteoporosis and Prognosis of Elderly Diabetic Patients Treated with SGLT-2 Inhibitors
赵宇洁 1肖童 1王丽1
作者信息
- 1. 河南省胸科医院内分泌与老年病科,河南郑州 450003
- 折叠
摘要
Abstract
Objective To explore the application value of bone mineral density(BMD)detected by quantitative CT(QCT)in evaluating osteoporosis and prognosis of elderly diabetic patients treated with SGLT-2 inhibitors.Methods A total of 100 elderly diabetic patients admitted to our hospital from January 2018 to June 2022 were selected and divided into the SGLT-2 group and non-SGLT-2 group according to whether SGLT-2 inhibitors were used.The BMD was compared between the two groups,and the BMD was compared between patients with different prognosis in SGLT-2 group.Results The comparison of L1,L2,L3 and L1～L3 BMD before and after treatment showed no significant difference in SGLT-2 group(P＞0.05).No significant difference was found in BMD of L1,L2,L3 and L1～L3 after treatment between the SGLT-2 group and the non-SGLT-2 group(P＞0.05).In SGLT-2 group,the BMD of L1,L2,L3 and L1～L3 in patients with poor prognosis were significantly lower than those in patients with good prognosis(P＜0.05).Conclusions The impact of SCLT-2 inhibitors on BMD in elderly patients with diabetes may be mild.The use of QCT to measure BMD can early detect the potential risk of osteoporosis and fracture of patients,and can be used for prognostic evaluation.关键词
定量CT/糖尿病/SGLT-2抑制剂/骨质疏松/预后Key words
Quantitative CT/Diabetes/SGLT-2 inhibitor/Osteoporosis/Prognosis分类
医药卫生引用本文复制引用
赵宇洁,肖童,王丽..QCT骨密度测定对应用SGLT-2抑制剂的老年糖尿病患者骨质疏松和预后的评估[J].临床医学工程,2024,31(6):663-664,2.
