临床医学工程2024,Vol.31Issue(6):675-676,2.DOI:10.3969/j.issn.1674-4659.2024.06.0675
维生素D联合胸腺肽辅助治疗急性加重期COPD患者的临床研究
Clinical Study of Vitamin D Combined with Thymosin in the Adjuvant Treatment of Patients with Acute Exacerbation of COPD
尹士营 1贾祖强1
作者信息
- 1. 濮阳惠民医院呼吸内科,河南濮阳 457000
- 折叠
摘要
Abstract
Objective To explore the clinical effect of vitamin D combined with thymosin in the adjuvant treatment of patients with acute exacerbation of chronic obstructive pulmonary disease(COPD).Methods 80 patients with acute exacerbation of COPD were randomly divided into two groups.On the basis of conventional treatment,the control group was given thymosin adjuvant therapy,and the observation group was given vitamin D combined with thymosin adjuvant therapy.The therapeutic effect,arterial blood gas indicators and serum inflammatory factors were compared between the two groups.Results The total effective rate of treatment in the observation group was 97.50%,significantly higher than 85.00%in the control group(P<0.05).After treatment,the level of PaO2 in the observation group was significantly higher than that in the control group,and the levels of PaCO2,IL-6 and TNF-α were significantly lower than those in the control group(P<0.05).Conclusions Vitamin D combined with thymosin in the adjuvant treatment of acute exacerbation of COPD has significant effect,which can obviously improve the arterial blood gas indicators and relieve the inflammatory response of patients.关键词
慢性阻塞性肺疾病/胸腺肽/维生素D/动脉血气指标/炎性因子Key words
Chronic obstructive pulmonary disease/Thymosin/Vitamin D/Arterial blood gas indicator/Inflammatory factor分类
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尹士营,贾祖强..维生素D联合胸腺肽辅助治疗急性加重期COPD患者的临床研究[J].临床医学工程,2024,31(6):675-676,2.