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首页|期刊导航|中国医药科学|中性粒细胞与淋巴细胞比值联合梗死体积对醒后卒中前循环取栓的预测价值

中性粒细胞与淋巴细胞比值联合梗死体积对醒后卒中前循环取栓的预测价值

梁炳松 李育英 张岐平 陈英道

中国医药科学2024,Vol.14Issue(10):140-143,161,5.
中国医药科学2024,Vol.14Issue(10):140-143,161,5.DOI:10.20116/j.issn2095-0616.2024.10.34

中性粒细胞与淋巴细胞比值联合梗死体积对醒后卒中前循环取栓的预测价值

Predictive value of neutrophil-lymphocyte ratio combined with infarct volume on thrombectomy for anterior circulation wake-up stroke

梁炳松 1李育英 1张岐平 1陈英道1

作者信息

  • 1. 广西医科大学第七附属医院神经内科,广西梧州 543001
  • 折叠

摘要

Abstract

Objective To explore the predictive value of preoperative neutrophil-lymphocyte ratio(NLR)combined with infarct volume on the prognosis of thrombectomy for anterior circulation wake-up stroke.Methods The clinical data of 115 stroke patients admitted to the Seventh Affiliated Hospital of Guangxi Medical University from June 2018 to June 2023 were retrospectively included.The 90-day modified Rankin scale(mRS)score was taken as the dependent variable.Cases with mRS score 0-2 were included in the good prognosis group and cases with mRS score 3-5 were included in the poor prognosis group.Univariate and multivariate logistic regression were used to analyze the related factors,and the receiver operating characteristic(ROC)curve was adopted to evaluate the value and efficacy of NLR combined with infarct volume in predicting thrombectomy for stroke.Results Univariate analysis showed that there were significant differences in age,national institutes of health stroke scale(NIHSS)score at admission(baseline),infarct volume,collateral circulation assessed by digital subtraction angiography(DSA)and preoperative NLR(P<0.05).Multivariate logistic regression analysis showed that higher preoperative NLR and larger infarct volume were related to the adverse outcome after thrombectomy(P<0.05).ROC curve analysis showed that the areas under the curves of NLR and infarct volume were 0.644 and 0.783,respectively,and the area under the curve of the combination of the above two indexes was 0.827,with statistical difference(P<0.05).The predictive sensitivity was 66.02%and the predictive specificity was 87.53%.Conclusion The combination of preoperative NLR and core infarct volume can better predict the adverse outcome after embolectomy for anterior circulation wake-up stroke,which is helpful to judge the prognosis.Therefore,it is of certain clinical value.

关键词

醒后卒中/前循环/血管取栓/中性粒细胞与淋巴细胞比值/梗死体积/临床预测

Key words

Wake-up stroke/Anterior circulation/Endovascular thrombectomy/Neutrophil-lymphocyte ratio/Infarct volume/Clinical prediction

分类

医药卫生

引用本文复制引用

梁炳松,李育英,张岐平,陈英道..中性粒细胞与淋巴细胞比值联合梗死体积对醒后卒中前循环取栓的预测价值[J].中国医药科学,2024,14(10):140-143,161,5.

基金项目

广西壮族自治区卫生健康委员会科研课题(Z20211202) (Z20211202)

广西壮族自治区梧州市卫生健康委员会科研课题(WZWS-G2022011). (WZWS-G2022011)

中国医药科学

2095-0616

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