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新型缓释香囊的制备及释药规律

马小花 展学孔 傅健英 王芳 郑利锋

中国药物经济学2024,Vol.19Issue(5):101-104,4.
中国药物经济学2024,Vol.19Issue(5):101-104,4.DOI:10.12010/j.issn.1673-5846.2024.05.018

新型缓释香囊的制备及释药规律

Preparation and Drug Release Rule of A New Type of Sustained-release Perfume Bag

马小花 1展学孔 2傅健英 1王芳 1郑利锋1

作者信息

  • 1. 海南卫生健康职业学院,海口 570311
  • 2. 海口市保健酒工程技术开发研究中心,海口 570311
  • 折叠

摘要

Abstract

Objective To explore the preparation and drug release rule of a new type of sustained-release sachet.Methods Taking the new sustained-release sachet as the research object,the volatile oil content was determined by UV spectrophotometry using trichloromethane extraction method,in order to study the release curve and pattern of the new sustained-release capsule.Results There is a good linear relationship between the concentration of volatile oil and absorbance in the range of 0.1~1.8 mg/100 ml.The concentration of volatile oil in the sustained-release capsule showed a nonlinear decreasing trend with the extension of time,and the change trend of volatile oil in the decreasing process was from fast to slow,and the release speed was significantly slowed down at 10 d.Conclusion The new sustained-release sachet can have a slow release effect.

关键词

香囊/芳香中药/缓控释技术/释药曲线

Key words

Sachet/Aromatic traditional Chinese medicine/Slow and controlled release technology/Drug release curve

分类

医药卫生

引用本文复制引用

马小花,展学孔,傅健英,王芳,郑利锋..新型缓释香囊的制备及释药规律[J].中国药物经济学,2024,19(5):101-104,4.

基金项目

2021年海南省自然科学基金高层次人才项目(821RC1080) (821RC1080)

中国药物经济学

1673-5846

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