中国医药科学2024，Vol.14Issue(10)：21-25,5.DOI:10.20116/j.issn2095-0616.2024.10.05
系统生物学在中药成分抗肝纤维化中的研究进展
Research progress of systems biology in anti-hepatic fibrosis of traditional Chinese medicine components
摘要
Abstract
As a necessary stage for chronic liver injury to develop into cirrhosis or even liver cancer,with complex pathological and physiological processes,hepatic fibrosis is a difficulty in the field of liver disease treatment today.Traditional Chinese medicine(TCM)has unique advantages in treating hepatic fibrosis by focusing on overall conditioning,taking pathogenesis as a basis,and treating according to syndrome differentiation.The systematic integration research method of systems biology coincides with the holistic treatment concept of TCM.The research method of omics is applied in systems biology to explore the pathological mechanism and treatment strategy of hepatic fibrosis,which provides a new research idea for finding ideal anti-hepatic fibrosis treatment methods and targeted drugs.In this paper,the research and application of systems biology methods in anti-hepatic fibrosis of TCM in recent years are reviewed.关键词
肝纤维化/中医药/系统生物学/组学Key words
Hepatic fibrosis/Traditional Chinese medicine/Systems biology/Omics分类
医药卫生引用本文复制引用
申敏,蔡良良,钱莉..系统生物学在中药成分抗肝纤维化中的研究进展[J].中国医药科学,2024,14(10):21-25,5.基金项目
江苏省基础研究计划自然科学基金青年基金项目(BK20230588) （BK20230588）
江苏省高等学校基础科学(自然科学)研究面上项目(23KJB310031) （自然科学）
扬州市自然科学基金(YZ2023165). （YZ2023165）
