广州化学2024，Vol.49Issue(3)：66-69,4.DOI:10.16560/j.cnki.gzhx.20240316
优化液质法测定多种基质中五氯酚残留量
LC-MS for the Determination of Pentachlorophenol Residues in a Variety of Matrices
廖伟杰 1黄兆翔 1高佳敏1
作者信息
- 1. 中科检测技术服务(广州)股份有限公司,广东 广州 510520
- 折叠
摘要
Abstract
On the basis of GB 23200.92-2016"Determination of pentachlorophenol residues in foods of animal origin liquid chromatography-mass spectrometry",the pretreatment conditions were improved,using 1% ammonia water and acetonitrile to extract,QuEChERS method to purify,methanol after nitrogen blowing reconstitute.The results showed that the method could pass the methodological verification in various matrices,and the average recovery rate was 72.22%～89.51%.The precision test was performed separately,and the relative standard deviation(RSD)was 4.23%～10.28%(n=6),the linear relationship in the range(1～10 μg/L)is outstanding(correlation coefficient R>0.995),the quantification limit is 1.0 μg/kg,and the signal-to-noise ratio is greater than 10.The method can save the time spent on pretreatment,and reduce some costs.关键词
五氯酚/高效液相色谱串联质谱仪/基质效应/方法学验证/QuEChERS法Key words
pentachlorophenol/high performance liquid chromatography tandem mass spectrometer/matrix effect/methodological validation/QuEChERS method分类
化学化工引用本文复制引用
廖伟杰,黄兆翔,高佳敏..优化液质法测定多种基质中五氯酚残留量[J].广州化学,2024,49(3):66-69,4.
