工业微生物2024，Vol.54Issue(3)：98-104,7.DOI:10.3969/j.issn.1001-6678.2024.03.029
复合益生菌抗氧化和免疫增强作用的研究
Study on Antioxidant and Immune-enhancing Effects of Compound Probiotics
王诚 1孔德玲 1董桂红 1王玲 1范秋苹 1丁博群1
作者信息
- 1. 山东健源生物科技有限公司,山东泰安 271000
- 折叠
摘要
Abstract
The article aimed to investigate the effects of compound probiotics on antioxidant and immune enhancement in animals.Specifically,the SPF grade mice were treated by gavage,and serum biochemical indexes,antioxidant and immune of mice were detected.After that,compound probiotics were used as feed additives in dairy cow production and breeding,and physiological indexes of dairy cow serum were detected.The results showed that compound probiotics significantly reduced the contents of alanine aminotransferase(ALT),aspartate aminotransferase(AST),creatinine(CREA)and urea in immunocompromised mice(P＜0.05),and significantly increased the spleen index and thymus index(P＜0.05).In addition to the content of triglyceride,the contents of high density lipoprotein,low density lipoprotein,glucose,total protein,albumin and cholesterol were significantly increased after feeding the diet supplemented with compound probiotics(P＜0.05),the immune indexes of IgA,IgG and IgM in dairy cow serum were significantly increased(P＜0.05),the pro-inflammatory factor TNF-α was significantly decreased(P＜0.05),serum superoxide dismutase(SOD),glutathione peroxidase(GSH-Px)and catalase(CAT)indexes were significantly increased(P＜0.05)and the content of malondialdehyde(MDA)was significantly decreased(P＜0.05).Tests on mice and dairy cows have proved that the compound probiotics play a positive role in improving the health of animals,including the improvement of serum biochemical indexes within the normal range,the enhancement of antioxidant capacity and the enhancement of immunity.关键词
复合益生菌/血清生化指标/抗氧化/免疫性能Key words
compound probiotics/serum biochemical indicators/antioxidant/immune properties引用本文复制引用
王诚,孔德玲,董桂红,王玲,范秋苹,丁博群..复合益生菌抗氧化和免疫增强作用的研究[J].工业微生物,2024,54(3):98-104,7.
