海南医学院学报2024，Vol.30Issue(12)：947-951,5.DOI:10.13210/j.cnki.jhmu.20231208.001
影响多发性骨髓瘤预后的分子生物学异常研究进展
Research advances in molecular biological abnormalities affecting the prognosis of multiple myeloma
摘要
Abstract
Multiple myeloma is a plasma cell tumor characterized by monoclonal plasma cell dysplasia and multifocal bone in-volvement.It mainly occurs in middle-aged and elderly people.Although proteasome inhibitors,immunomodulators and hemato-poietic stem cell transplantation have improved the survival rate of patients,MM is still incurable.In recent years,due to the wide application of molecular biological detection technologies such as karyotype analysis,FISH,flow cytometry,liquid biopsy,etc.,the diagnostic rate of MM has been greatly improved.At the same time,many gene abnormalities related to the prognosis of MM have been found successively.关键词
多发性骨髓瘤/基因异常/预后Key words
Multiple myeloma/Genetic abnormality/Prognosis分类
医药卫生引用本文复制引用
李妙雨,高娅娅,高广勋..影响多发性骨髓瘤预后的分子生物学异常研究进展[J].海南医学院学报,2024,30(12):947-951,5.基金项目
National Natural Science Foundation of China project(81970190) （81970190）
Shaanxi Province Social Development and Public Relations Key Project(2019ZDLSF02-02) （2019ZDLSF02-02）
National Medical Center Transformation Project(2020ZKMC01)国家自然科学基金项目(81970190) （2020ZKMC01）
陕西省社发公关重点项目(2019ZDLSF02-02) （2019ZDLSF02-02）
国家医学中心转化课题(2020ZKMC01) （2020ZKMC01）
