机器人外科学杂志（中英文）2024，Vol.5Issue(3)：347-354,8.DOI:10.12180/j.issn.2096-7721.2024.03.007
超声引导下星状神经节阻滞对机器人辅助腹腔镜下前列腺癌根治术患者术中应激反应水平及术后认知功能恢复情况的影响
Effect of ultrasound-guided SGB on the intraoperative stress response level and postoperative cognitive function recovery of patients undergoing robot-assisted laparoscopic radical prostatectomy
摘要
Abstract
Objective:To investigate the effect of ultrasound-guided stellate ganglion block(SGB)on intraoperative stress response level and postoperative cognitive function in patients undergoing robot-assisted laparoscopic radical prostatectomy(RALRP).Methods:78 patients who underwent RALRP in Taihe hospital from January 2020 to December 2022 were randomly divided into the study group and the control group,with 39 cases in each group.The study group received ultrasound-guided SGB,while the control group received normal saline injection only.During the perioperative period,the life indicators and blood indexes of patients were recorded after entering the room(T0),tracheal intubation(T1),pneumoperitoneum(T2),10 minutes after operation started(T3),20 minutes after operation started(T4),the end of operation(T5),and 2 hours after surgery(T6).The stress response indicators(including cortisol and epinephrine)and MMSE scores of patients at different time points were compared between the two groups.Results:From T0 to T5,the heart rate and diastolic blood pressure in the two groups showed a trend of decreasing,and the systdic pressure showed a trend of decreasing to increasing,but the systolic pressure at T5 was lower than that at T0,while SpO2 increased first and then decreased to its primary level,and the differences were statistically significant at different time points(P<0.05),but there was no significant difference in perioperative indicators between the two groups at the same time point(P>0.05).From T2 to T6,the levels of cortisol and epinephrine in the two groups increased at first and then decreased(P<0.05).The levels of cortisol and epinephrine in the study group at T2,T4 and T6 were lower than those in the control group(P<0.05).From preparation to 5 days after surgery,the MMSE scores of patients in the two groups showed a trend of decreasing to increasing to decreasing in a small range,and the difference were statistically significant at different time points(P<0.05),but the MMSE scores of the two groups of patients at the same time point were not significantly different(P>0.05).The incidence of cognitive impairment was 5.13%(2/39)in the study group and 20.51%(8/39)in the control group 3 days after surgery,and the difference was statistically significant(P<0.05).Conclusion:Ultrasound guided SGB can stabilize the vital signs of patients in RALRP,lower the intraoperative stress response level,and accelerate the postoperative recovery of cognitive function.关键词
机器人辅助手术/前列腺癌根治术/星状神经节阻滞/超声/应激反应/认知功能Key words
Robot-assisted Surgery/Radical Prostatectomy/Stellate Ganglion Block/Ultrasound/Stress Response/Cognitive Function分类
医药卫生引用本文复制引用
孙艳芳,黄敏,宋晓雨,魏妮..超声引导下星状神经节阻滞对机器人辅助腹腔镜下前列腺癌根治术患者术中应激反应水平及术后认知功能恢复情况的影响[J].机器人外科学杂志（中英文）,2024,5(3):347-354,8.基金项目
湖北省卫生健康委员会科研专项(WJ2020M255) （WJ2020M255）
武汉市医学科研项目(WX21C31) Research Project of Health Commission of Hubei Province(WJ2020M255) （WX21C31）
Medical Research Project of Wuhan City(WX21C31) （WX21C31）
