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α-酮戊二酸的生理功能及其在口腔医学领域的研究进展

程楚男 胡丹丹 康非吾

口腔颌面外科杂志2024,Vol.34Issue(3):231-233,3.
口腔颌面外科杂志2024,Vol.34Issue(3):231-233,3.DOI:10.12439/kqhm.1005-4979.2024.03.011

α-酮戊二酸的生理功能及其在口腔医学领域的研究进展

The physiological function of α-ketoglutarate acid and its research advances in stomatology

程楚男 1胡丹丹 1康非吾1

作者信息

  • 1. 同济大学附属口腔医院口腔颌面外科,同济大学口腔医学院,上海牙组织修复与再生工程技术研究中心,同济大学口腔医学研究所,上海 200072
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摘要

Abstract

α-ketoglutarate acid(AKG)is an essential intermediary metabolite of the tricarboxylic acid(TCA)cycle and amino acid metabolism.By participating in the generation of adenosine-triphosphate(ATP)and the biosynthesis of a variety of important amino acids and proteins,it is widely involved in a series of important physiological processes.Since there are few reports on the research of AKG in stomatology,this paper reviews the physiological function of AKG and its research advances in stomatology,which may lay a theoretical foundation for broadening the application of AKG in stomatology.

关键词

α-酮戊二酸/骨代谢/表观遗传学/免疫调节

Key words

α-ketoglutarate acid/bone metabolism/epigenetics/immune regulation

分类

医药卫生

引用本文复制引用

程楚男,胡丹丹,康非吾..α-酮戊二酸的生理功能及其在口腔医学领域的研究进展[J].口腔颌面外科杂志,2024,34(3):231-233,3.

基金项目

国家自然科学基金(82271013) (82271013)

口腔颌面外科杂志

OACSTPCD

1005-4979

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