口腔颌面外科杂志2024，Vol.34Issue(3)：234-237,4.DOI:10.12439/kqhm.1005-4979.2024.03.012
骨细胞对成骨细胞和破骨细胞的调控及机制的研究进展
Research progress on the regulation and mechanism of osteocytes on osteoblasts and osteoclasts
摘要
Abstract
With the continuous explorations and researches of osteocytes,osteocytes are no longer mistaken for a kind of quiescent and passive cells,but active and positive cells,which play important regulatory roles in osteoblasts and osteoclasts.While an increasing number of studies have identified key signaling pathways and crosstalk mechanisms related to osteocytes.To some extent,the role of osteocyte apoptosis and its complex mechanisms occurring in various states of pathologies are still not elucidated.If further studies can be performed,this will help to fully understand the function and mechanism of osteocytes in a variety of states,as well as provide a novel target for bone diseases.At present,there are many reports about osteocytes regulating osteoblasts and osteoclasts.In this paper,the research progresses in regulation and mechanism of osteoblasts and osteoclasts by osteocytes are reviewed.关键词
骨细胞/成骨细胞/破骨细胞/骨硬化蛋白/脉动流/凋亡Key words
osteocyte/osteoblast/osteoclast/sclerostin/pulsating fluid flow/apoptosis分类
医药卫生引用本文复制引用
杨镇鸣,张淑玉,强金彪,石琰,王晓玲,史册..骨细胞对成骨细胞和破骨细胞的调控及机制的研究进展[J].口腔颌面外科杂志,2024,34(3):234-237,4.基金项目
国家自然科学基金(82270959、81970903) （82270959、81970903）
