环境与职业医学2024，Vol.41Issue(6)：707-712,6.DOI:10.11836/JEOM24036
呼出气挥发性有机物的采集及分析方法研究进展
Research progress on collection and analysis methods of exhaled volatile organic compounds
摘要
Abstract
The composition and concentration of volatile organic compounds(VOCs)in exhaled breath are closely related to human health and the analysis of VOCs by collecting human exhaled breath has been widely used in disease surveillance research.This article reviewed the collection,en-richment,and detection methods of exhaled VOCs,which can provide a reference for selecting appropriate technology for follow-up research.The exhaled breath collection devices mainly in-clude sampling bags for mixed exhaled breath and biological volatile organic compound(Bio-VOC)samplers for alveolar air.The pre-enrichment equipment included thermal desorption(TD),solid-phase microextraction device(SPME),and needle trap device(NTD).The detection methods of exhaled VOCs include gas chromatography-mass spectrometry(GC-MS),proton transfer reac-tion mass spectrometry(PTR-MS),selective ion flow tube mass spectrometry(SIFT-MS),and electronic nose.At present,the collection and enrichment technology of exhaled breath is not mature yet,and its influence on the results of detection is lack of evaluation.In the future,the research on collection and enrichment technology of exhaled breath should be strengthened to further promote the application of exhaled breath in disease surveillance research.关键词
呼出气/挥发性有机物/采集/富集/检测Key words
exhaled breath/volatile organic compound/collection/enrichment/detection分类
医药卫生引用本文复制引用
何雅珍,高汭,吴智君,樊晶光,丁春光..呼出气挥发性有机物的采集及分析方法研究进展[J].环境与职业医学,2024,41(6):707-712,6.基金项目
国家卫生健康委职业安全卫生研究中心自管项目(2019009) （2019009）
中央级公益性科研院所基本科研业务费(2020-PT320-005) （2020-PT320-005）
