自身免疫性胰腺炎的病理学诊断OA北大核心CSTPCD

Autoimmune pancreatitis(AIP)is a rare disease,and its diagnosis should be made based on a comprehensive evaluation of clinical,radiological,serological,and pathological findings.At present,AIP is classified into two subtypes of type 1(identified as the pancreatic manifestation of IgG4-related disease)and type 2(identified as the pancreas-specific disorder independent of IgG4).Although type 1 and type 2 AIP seem to have different pathogeneses,they tend to have similar radiological findings and exhibit a good response to corticosteroid therapy.This article mainly reviews the histopathological features of the two subtypes of AIP,especially the diagnostic challenges encountered in the interpretation of specimens obtained through endoscopic ultrasound-guided fine needle aspiration/biopsy,to as to help pathologists enhance the accuracy of the diagnosis of AIP.