兰州大学学报（医学版）2024，Vol.50Issue(5)：70-80,11.DOI:10.13885/j.issn.1000-2812.2024.05.010
干细胞与特发性肺纤维化领域研究热点的可视化分析
Research hotspots on stem cells in the field of idiopathic pulmonary fibrosis:A visual analysis
摘要
Abstract
Objective To visually analyze literature related to stem cells in the field of IPF using bibliometrics,identify the research hotspots and shortcomings in this field.Methods The Web of Science core collection was used to conduct a comprehensive literature search on stem cells in the field of IPF from 2003 to 2022.The obtained data was visually analyzed by VOSviewer 1.6.19 and Citespace 6.2.R4 software,enabling an explo-ration of publication trends across different years,countries/regions,institutions,authors and journals.Addi-tionally,a co-occurrence analysis of keywords and citation analysis were performed.Results A total of 637 ar-ticles were included,and the annual publications in this field exhibited a consistent upward trend.The US emerged as the leading contributor with the highest number of articles,while the University of Pittsburgh stood out as the most productive institution.The top three authors with the largest number of articles were Geiser Thomas,Han Xiaodong and Rojas Mauricio.Noble Paul W was identified as the most cited author.The American Journal of Respiratory and Critical Care Medicine was the most prominent journal for publi-cations.Analysis of research trends had revealed a shift in focus towards stem cell therapy for IPF after 2018,highlighting investigations into mechanisms,therapeutic potentials of MSCs,and new drugs.Conclusion The number of studies on stem cells in the field of IPF had been gradually increasing.There were numerous au-thors and institutions involved in this field of research,but relatively few high-yield ones.Therefore,it's neces-sary to strengthen collaboration between different authors,institutions,regions,and countries.The results of a hotspot analysis indicated that stem cell therapy offered a promising intervention for IPF patients.Howev-er,there were still issues in clinical application that need to be addressed,such as determining the optimal source of stem cells,the route and frequency of stem cell transplantation,as well as appropriate intervals be-tween transplantations.These factors were crucial in assessing the feasibility of stem cell therapy for IPF.关键词
特发性肺纤维化/干细胞/可视化分析/文献计量学Key words
idiopathic pulmonary fibrosis/stem cells/visual analysis/bibliometrics分类
医药卫生引用本文复制引用
王彩云,邱婉春,苟盼盼,蒋娜,雷泽林..干细胞与特发性肺纤维化领域研究热点的可视化分析[J].兰州大学学报（医学版）,2024,50(5):70-80,11.基金项目
国家自然科学基金资助项目(81960017) （81960017）
