临床肝胆病杂志2024,Vol.40Issue(6):1240-1247,8.DOI:10.12449/JCH240626
非酒精性脂肪性肝病多组学研究现状
Advances in the multi-omics research on nonalcoholic fatty liver disease
摘要
Abstract
The prevalence rate of nonalcoholic fatty liver disease(NAFLD)reaches up to 30%around the world,and the disease has a serious impact on human health and constitutes a public health burden.Due to difficulties in the diagnosis and monitoring of NAFLD,it is important to identify potential drug targets and biomarkers,and multi-omics techniques hold great promise in the search for early diagnostic markers,therapeutic targets,and outcome and prognostic assessment of NAFLD.This article reviews the research advances in multi-omics techniques in the field of NAFLD in recent years,in order to provide a richer theoretical basis and new strategies for the prevention and treatment of NAFLD.关键词
非酒精性脂肪性肝病/基因组学/蛋白质组学/代谢组学/胃肠道微生物组Key words
Non-alcoholic Fatty Liver Disease/Genomics/Proteomics/Metabolomics/Gastrointestinal Microbiome引用本文复制引用
段明秀,陈新利,常伟宇,杨媛,杨仕琦,吴晖..非酒精性脂肪性肝病多组学研究现状[J].临床肝胆病杂志,2024,40(6):1240-1247,8.基金项目
云南省应用基础研究专项项目(202301AT070152) Yunnan Province Applied Basic Research Special Project(202301AT070152) (202301AT070152)