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非酒精性脂肪性肝病多组学研究现状

段明秀 陈新利 常伟宇 杨媛 杨仕琦 吴晖

临床肝胆病杂志2024,Vol.40Issue(6):1240-1247,8.
临床肝胆病杂志2024,Vol.40Issue(6):1240-1247,8.DOI:10.12449/JCH240626

非酒精性脂肪性肝病多组学研究现状

Advances in the multi-omics research on nonalcoholic fatty liver disease

段明秀 1陈新利 1常伟宇 1杨媛 1杨仕琦 1吴晖1

作者信息

  • 1. 昆明医科大学第一附属医院临床药学中心,昆明 650000
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摘要

Abstract

The prevalence rate of nonalcoholic fatty liver disease(NAFLD)reaches up to 30%around the world,and the disease has a serious impact on human health and constitutes a public health burden.Due to difficulties in the diagnosis and monitoring of NAFLD,it is important to identify potential drug targets and biomarkers,and multi-omics techniques hold great promise in the search for early diagnostic markers,therapeutic targets,and outcome and prognostic assessment of NAFLD.This article reviews the research advances in multi-omics techniques in the field of NAFLD in recent years,in order to provide a richer theoretical basis and new strategies for the prevention and treatment of NAFLD.

关键词

非酒精性脂肪性肝病/基因组学/蛋白质组学/代谢组学/胃肠道微生物组

Key words

Non-alcoholic Fatty Liver Disease/Genomics/Proteomics/Metabolomics/Gastrointestinal Microbiome

引用本文复制引用

段明秀,陈新利,常伟宇,杨媛,杨仕琦,吴晖..非酒精性脂肪性肝病多组学研究现状[J].临床肝胆病杂志,2024,40(6):1240-1247,8.

基金项目

云南省应用基础研究专项项目(202301AT070152) Yunnan Province Applied Basic Research Special Project(202301AT070152) (202301AT070152)

临床肝胆病杂志

OA北大核心CSTPCD

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