临床肝胆病杂志2024,Vol.40Issue(6):1259-1263,5.DOI:10.12449/JCH240629
丙型肝炎持续病毒学应答后肝癌发生的危险因素及预测模型
Risk factors and predictive models for liver cancer after sustained virologic response in hepatitis C
摘要
Abstract
Hepatitis C is one of the main causes of liver cancer.With the application of direct-acting antiviral agents,more than 95%of patients can achieve the eradication of hepatitis C virus and obtain sustained virologic response(SVR).Effective antiviral therapy can change the natural course of hepatitis C and reduce the risk of liver cancer;however,some patients are still affected by age,sex,liver fibrosis,diabetes,hepatic steatosis,alcohol consumption,and genetic factors and become the high-risk population of liver cancer.Therefore,it is needed to further clarify and improve the identification and prediction of high-risk populations of liver cancer after SVR of hepatitis C.This article reviews the risk factors and predictive models for liver cancer after SVR in patients with hepatitis C,in order to provide a basis for identifying the high-risk population of liver cancer after SVR of hepatitis C in clinical practice.关键词
丙型肝炎/持续病毒学应答/肝肿瘤/危险因素Key words
Hepatitis C/Sustained Virologic Response/Liver Neoplasms/Risk Factors引用本文复制引用
许姗姗,仇丽霞,柳雅立,张晶..丙型肝炎持续病毒学应答后肝癌发生的危险因素及预测模型[J].临床肝胆病杂志,2024,40(6):1259-1263,5.基金项目
2022年度院内中青年人才孵育项目(BJYAYY-YN2022-02) Scientific Research Project of Beijing Youan Hospital,CCMU,2022(BJYAYY-YN2022-02) (BJYAYY-YN2022-02)