辽宁大学学报（自然科学版）2024，Vol.51Issue(2)：130-140,11.
基于AIE效应的内源性硫化氢荧光探针的研究进展
Progress in the Study of Endogenous Hydrogen Sulfide Fluorescent Probes Based on AIE Effect
刘冰弥 1宫达诚 2田璐 2生慧3
作者信息
- 1. 辽宁大学 药学院,辽宁 沈阳 110036||辽宁大学 司法鉴定研究院,辽宁 沈阳 110036||辽宁新药研发重点实验室,辽宁 沈阳 110036
- 2. 辽宁大学 药学院,辽宁 沈阳 110036
- 3. 辽宁大学 物理学院,辽宁 沈阳 110036
- 折叠
摘要
Abstract
Rational design of fluorescent probe molecules for monitoring endogenous hydrogen sulfide(H2 S)can help to fully understand its physiological and pathological functions.Most of the small-molecule fluorescent probes currently under development for the detection of H2 S suffer from aggregation-caused quenching(ACQ)effect,and the study of aggregation-induced emission(AIE)probes that can overcome this deficiency has received increasing attention.In this paper,we briefly review the progress and design ideas of chemically reactive H2 S in vivo imaging fluorescent probes with AIE effect in recent years,with the aim of providing some reference and thoughts for research in this field.关键词
内源性硫化氢/聚集诱导发光效应/聚集诱导猝灭效应/荧光探针/活体成像Key words
endogenous hydrogen sulfide/aggregation-caused quenching(ACQ)effect/aggregation-induced emission(AIE)effect/fluorescent probe/in vivo imaging分类
化学化工引用本文复制引用
刘冰弥,宫达诚,田璐,生慧..基于AIE效应的内源性硫化氢荧光探针的研究进展[J].辽宁大学学报（自然科学版）,2024,51(2):130-140,11.
