四川精神卫生2024，Vol.37Issue(3)：219-225,7.DOI:10.11886/scjsws20240202003
短程认知行为治疗改善精神分裂症患者生活质量的效果及影响因素
Efficacy of brief cognitive behavioral therapy on improving quality of life improvement in patients with schizophrenia
摘要
Abstract
Background The course of schizophrenia is prolonged,and patients have impaired social function and significantly reduced quality of life.Drug therapy combined with psychological therapy is particularly important for improving the quality of life of patients.Brief cognitive behavioral therapy(BCBT)has been widely applied in clinical practice,but current research on BCBT focuses more on improving patients' symptoms and lacks relevant reports on improving quality of life.Objective To evaluate the efficacy and influencing factors of BCBT combined with conventional treatment on improving the quality of life in patients with schizophrenia.Methods A total of 210 patients who met the diagnostic criteria for schizophrenia in the International Classification of Diseases(10th edition)(ICD-10)and were followed up at the outpatient department of Beijing Anding Hospital Capital Medical University from August 2011 to December 2016 were selected.Using a random number table method,patients were divided into study group and control group,with 105 cases in each group.Both groups received routine treatment,and the research group received a total of 8 BCBT sessions for 12 weeks on this basis.At the baseline period and 12 weeks of treatment,26 weeks of follow-up and 52 weeks of follow-up,Positive and Negative Syndrome Scale(PANSS),Personal and Social Performance Scale(PSP)and World Health Organization Quality of Life Brief(WHOQOL-BREF)were used for evaluation.Results The results of repeated measures analysis of variance showed that the time point effect and interaction effect of PANSS total score were statistically significant(F=118.783,8.083,P<0.01).The time point effect,inter group effect and interaction effect of PSP total score were statistically significant(F=94.358,4.048,5.490,P<0.05 or 0.01).The time point effect,inter group effect and interaction effect of the total score of WHOQOL-BREF were all statistically significant(F=12.330,4.168,4.142,P<0.05 or 0.01)Binary Logistic regression analysis showed that the study group(OR=1.861,95%CI:1.004～3.448)and young age(OR=1.044,95%CI:1.001～1.088)were protective factors for improving quality of life of patients,while high PANSS baseline score(OR=0.972,95%CI:0.945～0.999)was a risk factor for improving quality of life of patients.Conclusion The combination of BCBT and conventional treatment has an earlier onset of improvement in the quality of life of patients with schizophrenia,and long-term efficacy is superior to conventional treatment.关键词
精神分裂症/认知行为治疗/生活质量/影响因素Key words
Schizophrenia/Cognitive behavioral therapy/Quality of life/Influencing factors分类
临床医学引用本文复制引用
孙倩,杨晓婕,马云,郭志华,李占江..短程认知行为治疗改善精神分裂症患者生活质量的效果及影响因素[J].四川精神卫生,2024,37(3):219-225,7.基金项目
北京市科委资助科研项目(项目名称:首发精神分裂症患者认知行为治疗效果评价研究,项目编号:Z111107058811078) （项目名称:首发精神分裂症患者认知行为治疗效果评价研究,项目编号:Z111107058811078）
首都医学发展基金联合攻关项目(项目名称:精神分裂症社区CBT操作程式的效果评价研究,项目编号:2009-1050) （项目名称:精神分裂症社区CBT操作程式的效果评价研究,项目编号:2009-1050）
北京市卫生与健康科技成果和适宜技术推广项目(项目名称:短程认知行为治疗在精神分裂症社区康复中的推广,项目编号:TG-2017-38) Funded by Research Projects Supported by Beijing Municipal Commission of Science and Technology(number,Z111107058811078) （项目名称:短程认知行为治疗在精神分裂症社区康复中的推广,项目编号:TG-2017-38）
Capital Medical Development Fund Joint Research Project(number,2009-1050) （number,2009-1050）
Beijing Hygienism and Health Science and Technology Achievements and Appropriate Technology Promotion Project(number,TG-2017-38) （number,TG-2017-38）
