四川精神卫生2024,Vol.37Issue(3):267-269,3.DOI:10.11886/scjsws20240124001
强α1受体拮抗的非典型抗精神病药物导致精神分裂症患者自感发热不适1例
Atypical antipsychotic drugs with strong alpha 1 receptor antagonism resulting in self-perceived hot in patients with schizophrenia:a case report
孙林远 1高阳 2苏斌 2李名立1
作者信息
- 1. 四川大学华西医院,四川 成都 610041
- 2. 克拉玛依市中西医结合医院,新疆 克拉玛依 834000
- 折叠
摘要
Abstract
This article reported a case of a patient with schizophrenia who experienced self-perceived fever and discomfort after taking atypical antipsychotic drugs with strong alpha 1 receptor antagonism,which included olanzapine,risperidone,paliperidone and clozapine.Such phenomenon was believed to be a medication side effect.Therefore,the patient switched to aripiprazole and the fever disappeared.This case report is intended to remind psychiatrists to pay attention to the side effects caused by atypical antipsychotic drugs with strong alpha 1 receptor antagonism as well as to suggest that various factors should be considered,including mechanisms of drug action,patient pathophysiology and individual differences,in order to improve treatment compliance and prognosis.关键词
精神分裂症/强α1受体拮抗的非典型抗精神病药物/发热Key words
Schizophrenia/Atypical antipsychotic drugs with strong alpha 1 receptor antagonism/Fever分类
医药卫生引用本文复制引用
孙林远,高阳,苏斌,李名立..强α1受体拮抗的非典型抗精神病药物导致精神分裂症患者自感发热不适1例[J].四川精神卫生,2024,37(3):267-269,3.